Awareness of primary immunodeficiency diseases at a national pediatric reference center in Peru [PDF]
Einstein (São Paulo), 2021 Objective To investigate the level of awareness of primary immunodeficiency diseases among physicians working at Instituto Nacional de Salud del Niño.
Liz Eliana Veramendi-Espinoza +5 more
doaj +5 more sources
Gene therapy and genome editing for primary immunodeficiency diseases [PDF]
Genes and Diseases, 2020 In past two decades the gene therapy using genetic modified autologous hematopoietic stem cells (HSCs) transduced with the viral vector has become a promising alternative option for treating primary immunodeficiency diseases (PIDs).
Zhi-Yong Zhang +2 more
doaj +3 more sources
Impact of Primary Immunodeficiency Diseases on the Life Experiences of Patients in Malaysia From the Caregivers’ Perspective: A Qualitative Study [PDF]
Frontiers in Pediatrics, 2022 IntroductionPrimary immunodeficiency diseases (PIDs) are chronic diseases that affect the various aspects of a patient’s life. However, the impact of living with PIDs is poorly described.ObjectiveThis study aimed to explore the living experience ...
Ruwaydah Ahmed Meelad +10 more
doaj +2 more sources
Reversion Mosaicism in Primary Immunodeficiency Diseases [PDF]
Frontiers in Immunology, 2021 Reversion mosaicism has been reported in an increasing number of genetic disorders including primary immunodeficiency diseases. Several mechanisms can mediate somatic reversion of inherited mutations.
Hanae Miyazawa, Taizo Wada
doaj +2 more sources
Systematic Review of Primary Immunodeficiency Diseases in Malaysia: 1979–2020 [PDF]
Frontiers in Immunology, 2020 Introduction: Primary immunodeficiency diseases (PIDs) are under-reported in Malaysia. The actual disease frequency of PID in this country is unknown due to the absence of a national patient registry for PID.Objective: This systematic review aimed to ...
Intan Juliana Abd Hamid +5 more
doaj +2 more sources
Expanding TREC and KREC Utility in Primary Immunodeficiency Diseases Diagnosis [PDF]
Frontiers in Immunology, 2020 Primary immunodeficiency diseases (PID) area heterogeneous group of disorders caused by genetic defects of the immune system, which manifest clinically as recurrent infections, autoimmune diseases or malignancies.
Ilya Korsunskiy +23 more
doaj +2 more sources
Real-World Use, Safety, and Patient Experience of 20% Subcutaneous Immunoglobulin for Primary Immunodeficiency Diseases. [PDF]
Adv Ther, 2023 Fasshauer M +7 more
europepmc +3 more sources
Immunoglobulin therapies for primary immunodeficiency diseases (part 2): considerations for dosing strategies. [PDF]
ImmunotherapyLi Z, Mahmood I.
europepmc +3 more sources
Primary Immunodeficiency Diseases: Current and Emerging Therapeutics [PDF]
Frontiers in Immunology, 2017 Primary immunodeficiency diseases (PID) result from defects in genes affecting the immune and other systems in many and varied ways (1, 2). Until the last few years, treatments have been largely supportive, with the exception of bone marrow ...
Beatriz E. Marciano, Steven M. Holland
doaj +2 more sources
An updated review on phenocopies of primary immunodeficiency diseases [PDF]
Genes and Diseases, 2020 Primary immunodeficiency diseases (PIDs) refer to a heterogenous group of disorders characterized clinically by increased susceptibility to infections, autoimmunity and increased risk of malignancies.These group of disorders present with clinical ...
Ankita Singh +4 more
doaj +2 more sources