Reversion Mosaicism in Primary Immunodeficiency Diseases [PDF]
Frontiers in Immunology, 2021 Reversion mosaicism has been reported in an increasing number of genetic disorders including primary immunodeficiency diseases. Several mechanisms can mediate somatic reversion of inherited mutations.
Hanae Miyazawa, Taizo Wada
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Systematic Review of Primary Immunodeficiency Diseases in Malaysia: 1979–2020 [PDF]
Frontiers in Immunology, 2020 Introduction: Primary immunodeficiency diseases (PIDs) are under-reported in Malaysia. The actual disease frequency of PID in this country is unknown due to the absence of a national patient registry for PID.Objective: This systematic review aimed to ...
Intan Juliana Abd Hamid +5 more
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Expanding TREC and KREC Utility in Primary Immunodeficiency Diseases Diagnosis [PDF]
Frontiers in Immunology, 2020 Primary immunodeficiency diseases (PID) area heterogeneous group of disorders caused by genetic defects of the immune system, which manifest clinically as recurrent infections, autoimmune diseases or malignancies.
Ilya Korsunskiy +23 more
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Primary Immunodeficiency Diseases in COVID-19 Pandemic: A Predisposing or Protective Factor? [PDF]
Am J Med Sci, 2020 Babaha F, Rezaei N.
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Gene therapy and genome editing for primary immunodeficiency diseases [PDF]
Genes and Diseases, 2020 In past two decades the gene therapy using genetic modified autologous hematopoietic stem cells (HSCs) transduced with the viral vector has become a promising alternative option for treating primary immunodeficiency diseases (PIDs).
Zhi-Yong Zhang +2 more
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An updated review on phenocopies of primary immunodeficiency diseases [PDF]
Genes and Diseases, 2020 Primary immunodeficiency diseases (PIDs) refer to a heterogenous group of disorders characterized clinically by increased susceptibility to infections, autoimmunity and increased risk of malignancies.These group of disorders present with clinical ...
Ankita Singh +4 more
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Primary Immunodeficiency Diseases: Current and Emerging Therapeutics [PDF]
Frontiers in Immunology, 2017 Primary immunodeficiency diseases (PID) result from defects in genes affecting the immune and other systems in many and varied ways (1, 2). Until the last few years, treatments have been largely supportive, with the exception of bone marrow ...
Beatriz E. Marciano, Steven M. Holland
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CUTANEOUS MANIFESTATIONS OF PRIMARY IMMUNODEFICIENCY DISEASES IN TUNISIAN CHILDREN [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2018 . Skin manifestations are frequent among patients with primary immunodeficiency diseases (PIDs). Their prevalence varies according to the type of immunodeficiency.
Naouel GUIRAT +8 more
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A clinician's guide for administration of high-concentration and facilitated subcutaneous immunoglobulin replacement therapy in patients with primary immunodeficiency diseases. [PDF]
Allergy Asthma Clin Immunol, 2022 Immunoglobulin replacement therapy is the standard-of-care treatment for patients with primary immunodeficiency diseases who have impaired antibody production and function.
Epland K, Suez D, Paris K.
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International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity [PDF]
Journal of Clinical Immunology, 2017 Beginning in 1970, a committee was constituted under the auspices of the World Health Organization (WHO) to catalog primary immunodeficiencies. Twenty years later, the International Union of Immunological Societies (IUIS) took the remit of this committee.
Capucine Pïcard +19 more
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