Results 171 to 180 of about 357,974 (288)

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Immunoglobulin therapies for primary immunodeficiency diseases (part 2): considerations for dosing strategies. [PDF]

Immunotherapy
Li Z, Mahmood I.
europepmc   +1 more source

Rubella virus-associated chronic inflammation in primary immunodeficiency diseases. [PDF]

Curr Opin Allergy Clin Immunol, 2020
Perelygina L, Icenogle J, Sullivan KE.
europepmc   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study. [PDF]

Allergy Asthma Clin Immunol
Čižnár P, Roderick M, Schneiderova H, Jeseňák M, Kriván G, Brodszki N, Jolles S, Atisso C, Fielhauer K, Saeed-Khawaja S, McCoy B, Yel L.   +11 more
europepmc   +1 more source

Primary Immunodeficiency Diseases in COVID-19 Pandemic: A Predisposing or Protective Factor? [PDF]

Am J Med Sci, 2020
Babaha F, Rezaei N.
europepmc   +1 more source

Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting-Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases. [PDF]

Front Immunol, 2021
Sprenkeler EGG, Guenther C, Faisal I, Kuijpers TW, Fagerholm SC.   +4 more
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Mechanism and target treatment of primary immunodeficiency diseases with systemic lupus erythematosus-like phenotype. [PDF]

Pediatr Discov
Liu S, Zhang Z, Tang X, Zhao X, An Y.
europepmc   +1 more source