What Immunological Defects Predispose to Non-tuberculosis Mycobacterial Infections? [PDF]
Nontuberculous mycobacteria (NTM) are categorized as one of the large and diverse groups of environmental organisms which are abundant in water and soil. NTM cause a variety of diseases in humans that mainly affect the lung.
Adcock, IM+7 more
core
Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo+11 more
core +3 more sources
Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency. [PDF]
Adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is characterized by impaired T-, B- and NK-cell function. Affected children, in addition to early onset of infections, manifest non-immunologic symptoms including pulmonary ...
Candotti, Fabio+6 more
core +2 more sources
Клинические и лабораторные особенности случая общей вариабельной иммунной недостаточности [PDF]
Загальна варіабельна імунна недостатність (ЗВІН) є одним із найбільш розповсюджених первинних імунодефіцитів та характеризується порушенням продукції сироваткових імуноглобулінів IgG, IgM, IgA, а також специфічних антитіл.
Прилуцкая, И.С.+3 more
core
Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania. [PDF]
BACKGROUND: Cervical cancer is the leading cause of female cancer-related deaths in Tanzania. Vaccination against human papillomavirus (HPV) offers a new opportunity to control this disease.
Quentin, Wilm+9 more
core +5 more sources
Primary Immunodeficiency Diseases
Part I Overview: Ochs, Smith, Puck, molecular approaches to primary immune disoders Puck, genetics Sprangrude, mammalian haematopoietic development and function Tak Mak, T cell development Rolink, Andersson, Ghia, Grawunder, Kalberer, Karasuyama, Oka, Ten Boekel, Winkler, Melcher, molecular mechanisms guiding B cell development Weiss, DeFranco, signal ...
Reith, Walter+2 more
openaire +3 more sources
HCV epidemiology in high-risk groups and the risk of reinfection [PDF]
Injecting risk behaviours among people who inject drugs (PWID) and high-risk sexual practices among men who have sex with men (MSM) are important routes of hepatitis C virus (HCV) transmission.
Dalgard, Olav+6 more
core +2 more sources
PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]
Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy+3 more
core +4 more sources
Neutropenia in Primary Immunodeficiency Diseases
Phagocytes including neutrophil granulocytes and macrophages are important cells of the innate immune system whose primary function is to ingest and destroy microorganisms. Neutrophils help their host fight infections by phagocytosis, degranulation, and neutrophil extracellular traps.
openaire +4 more sources
Monogenic polyautoimmunity in primary immunodeficiency diseases
Primary immunodeficiency diseases (PIDs) consist of a large group of genetic disorders that affect distinct components of the immune system. PID patients are susceptible to infection and non-infectious complications, particularly autoimmunity. A specific group of monogenic PIDs are due to mutations in genes that are critical for the regulation of ...
Azizi G.+6 more
openaire +3 more sources