Results 31 to 40 of about 12,518 (225)

Overlap of Primary Membranous Nephropathy, IgA Nephropathy, and Diabetic Nephropathy: A Case Report

Cureus, 2023
The coexistence of primary membranous nephropathy (PMN), immunoglobulin A nephropathy (IgAN), and diabetic nephropathy (DN) in the same patient has been a subject of clinical and pathological investigation, yielding inconclusive results. The limited availability of cases and resource materials has hindered a comprehensive understanding of this ...
openaire   +2 more sources

Distribution of glomerular diseases in Taiwan: preliminary report of National Renal Biopsy Registry–publication on behalf of Taiwan Society of Nephrology

BMC Nephrology, 2018
Background Despite the development of biomarkers and noninvasive imaging tools, biopsy remains the only method for correctly diagnosing patients with unexplained hematuria, proteinuria and renal failure.
Hsien-Fu Chiu, Hung-chun Chen, Kuo-Cheng Lu, Kuo-Hsiung Shu, Taiwan Society of Nephrology   +4 more
doaj   +1 more source

Primary membranous glomerulonephritis-associated with schistosomal nephropathy

Indian Journal of Nephrology, 2019
The association of bilharziasis with membranous nephropathy (MN) has long been debated. The relatively recent use of antibodies against the M-type phospholipase A2 receptor (PLA2R) has been proposed as a valuable tool to discriminate the idiopathic from secondary MNs.
Mohammad Ibrahim, Walaa Hosny, Aly, Mostafa Gaafar, Abdo, Marwa Kamal, Ismail, Wesam   +3 more
openaire   +2 more sources

Immune-Monitoring Disease Activity in Primary Membranous Nephropathy [PDF]

Frontiers in Medicine, 2019
Primary membranous nephropathy (MN) is a glomerular disease mediated by autoreactive antibodies, being the main cause of nephrotic syndrome among adult patients. While the pathogenesis of MN is still controversial, the detection of autoantibodies against two specific glomerular antigens, phospholipase A2 receptor (PLA2R) and thrombospondin type 1 ...
Paolo Cravedi, Marta Jarque, Andrea Angeletti, Àlex Favà, Chiara Cantarelli, Oriol Bestard, Oriol Bestard   +6 more
openaire   +5 more sources

Designing Clinical Trials for the Treatment of Membranous Nephropathy in the Anti-Phospholipase A2 Receptor 1 Era: Results of a NephCure Membranous Nephropathy Workshop

Glomerular Diseases
Primary membranous nephropathy is a common cause of adult-onset nephrotic syndrome, with an overall incidence of 12 cases per million per year.
Marco Prunotto, Patrick H. Nachman, Barbara S. Gillespie, Laurence H. Beck, Aliza M. Thompson, Austin H. Hu, Elizabeth A. Stafford, Josh M. Tarnoff, Brad H. Rovin   +8 more
doaj   +1 more source

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy

Frontiers in Immunology, 2018
Membranous nephropathy is an immune kidney disease caused by IgG antibodies that form glomerular subepithelial immune complexes. Proteinuria is mediated by complement activation, as a result of podocyte injury by C5b-9, but the role of specific ...
Wentian Luo, Wentian Luo, Florina Olaru, Florina Olaru, Jeffrey H. Miner, Laurence H. Beck, Johan van der Vlag, Joshua M. Thurman, Dorin-Bogdan Borza, Dorin-Bogdan Borza   +9 more
doaj   +1 more source

Prognostic Factors of Proteinuria Remission in Primary Membranous Nephropathy. [PDF]

J Clin Med
Primary membranous nephropathy is a leading cause of nephrotic syndrome in adults, characterized by immune complex deposition in the glomerular basement membrane. Predicting proteinuria remission is essential for guiding treatment decisions, optimizing immunosuppressive therapy, and improving renal outcomes. Traditional prognostic markers, such as anti-
Krakowska-Jura K, Kler AN, Wajerowska W, Konieczny A, Banasik M.   +4 more
europepmc   +3 more sources

Tacrolimus-induced epilepsy with primary membranous nephropathy

Medicine, 2021
Abstract Rationale: Tacrolimus-associated neurologic disorders can be found in some cases, mainly in organ transplantation patients. However, epilepsy induced by tacrolimus in primary membranous nephropathy (PMN) patient is scare.
Yang, Yan, Zhang, Lei, Mo, Ying, Ren, Rong, Wang, Fengmei   +4 more
openaire   +2 more sources

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

Advanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li, Chaoyang Hua, Guangpu Li, Furong Zhai, Jingjing Ren, Shaokang Pan, Qi Feng, Jianguo Wen, Dongwei Liu, Zhangsuo Liu, Jiayu Duan   +10 more
wiley   +1 more source

Recurrent Membranous Nephropathy Management after Kidney Transplant: A Case Report

مجله علمی دانشگاه علوم پزشکی کردستان, 2023
Background and Aim: Membranous nephropathy (MN) is a podocytopathy characterized histologically by uniform thickening of the glomerular basement membrane due to the presence of subepithelial immune deposits.
Mohammad saad forghani, Hormat Rahimzadeh, Mahmoud Parvin, anvar mohammadi   +3 more
doaj