Results 31 to 40 of about 12,666 (271)

Treatment of membranous nephropathy: Perspectives on current and future therapies

Frontiers in Nephrology, 2023
Primary membranous nephropathy remains one of the most frequent causes of nephrotic syndrome in adults. It is an autoimmune disorder in which auto-antibodies target antigens at the podocytes cell membrane–basement membrane interface. Our understanding of
Monarch Shah, Andrew DeLaat, Corey Cavanaugh   +2 more
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The value of repeat kidney biopsy during an atypical course of membranous nephropathy

BMC Nephrology, 2022
Background The clinical trajectory for patients with primary membranous nephropathy ranges widely from spontaneous remission to a rapid decline in kidney function.
Sumaiya Ahmed, David Massicotte-Azarniouch, Mark Canney, Clare Booth, Paula Blanco, Gregory L. Hundemer   +5 more
doaj   +1 more source

Primary Membranous Nephropathy [PDF]

Clinical Journal of the American Society of Nephrology, 2017
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are renal limited (primary MN, PMN) and 20% are associated with other systemic diseases or exposures (secondary MN). This review focuses only on PMN.
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Primary Membranous Nephropathy - what do we know today?

, 2023
Introduction: Primary membranous nephropathy (PMN) is a common cause of nephrotic syndrome in adults, characterized by the deposition of immune complexes in the glomerular basement membrane.
Marcin Wais, Adam Jasiura, Aleksandra Wójcik, Kamila Giżewska, Konrad Warchoł   +4 more
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Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?

PLoS ONE, 2023
Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy.
Omar Ragy, Vilma Rautemaa, Alison Smith, Paul Brenchley, Durga Kanigicherla, Patrick Hamilton   +5 more
doaj   +2 more sources

Profile and primary treatment outcomes in membranous nephropathy

Saudi Medical Journal, 2022
To assess the clinical profile and primary treatment response and outcomes in idiopathic membranous nephropathy (IMN) patients.This study was carried out between December 2013 and January 2019 in a tertiary care hospital in North India on 2 years retrospective and 3 years prospective renal biopsy proven patients with IMN presenting with nephrotic ...
Hemanth Kumar, M.K., Sandhu, Jashan, Sandhu, Jasvinder S.   +2 more
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Profile of Primary Membranous Nephropathy among Membranous Nephropathy Patients Based on PLA2 Receptor Staining in Biopsy [PDF]

, 2021
INTRODUCTION: Membranous nephropathy is one of the common cause of nephrotic syndrome in adults. MN usually presents with nephrotic syndrome or heavy proteinuria, while renal function is often normal or near normal. Disease progression is variable, with
Mohamed Aaseem Arshad, V S
core  

Rituximab Therapy for Primary Membranous Nephropathy in a Chinese Cohort [PDF]

Frontiers in Medicine, 2021
Background: Rituximab has become one of the first-line therapies for the treatment of moderate and high-risk primary membranous nephropathy (pMN). We retrospectively reviewed 95 patients with pMN who received rituximab therapy and focused on the therapeutic effects and safety of this therapy in a Chinese cohort.Methods: Ninety-five consecutive patients
Shuang Gao, Shuang Gao, Shuang Gao, Shuang Gao, Zhao Cui, Zhao Cui, Zhao Cui, Zhao Cui, Xin Wang, Xin Wang, Xin Wang, Xin Wang, Yi-miao Zhang, Yi-miao Zhang, Yi-miao Zhang, Yi-miao Zhang, Fang Wang, Fang Wang, Fang Wang, Fang Wang, Xu-yang Cheng, Xu-yang Cheng, Xu-yang Cheng, Xu-yang Cheng, Li-qiang Meng, Li-qiang Meng, Li-qiang Meng, Li-qiang Meng, Fu-de Zhou, Fu-de Zhou, Fu-de Zhou, Fu-de Zhou, Gang Liu, Gang Liu, Gang Liu, Gang Liu, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao   +40 more
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Clinical Phenotypes and Predictors of Remission in Primary Membranous Nephropathy [PDF]

Journal of Clinical Medicine, 2021
(1) Background: We sought to investigate the clinical outcome and to identify the independent predictors of clinical remission in a prospectively followed cohort of patients with primary membranous nephropathy (pMN). (2) Methods: We conducted a prospective, observational, non-interventional study that included 65 consecutive patients diagnosed with pMN
Roxana Jurubiță, Bogdan Obrișcă, Bogdan Sorohan, Camelia Achim, Georgia Elena Micu, Gabriel Mircescu, Gener Ismail   +6 more
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HLA-D and PLA2R1 risk alleles associate with recurrent primary membranous nephropathy in kidney transplant recipients

, 2020
Recurrence of primary membranous nephropathy after transplantation occurs in up to 44% of patients and is driven by PLA2R antibody. Here, we asked whether genetic determinants could improve risk prediction.
Hourmant, Maryvonne, Tesar, Vladimir, Viklický, Ondrej, Brenchley, Paul; id_orcid, Mousson, Christiane, Wetzels, Jack, Dubois, V., Debiec, Hanna, Choukroun, Gabriel, Gandhi, Manish J., Guibert, Sylvain, Mrázová, Petra, Hourmant, M., Brenchley, P., Cruzado, Josep Maria, Debiec, H., Tesar, V., Gandhi, Manish,, Vuiblet, Vincent, Moyer, Ann,, Levi, C., Guibert, S. de, Ronco, P., Mrázová, P., Moyer, Ann M., Letouzé, Eric, Berchtold, L., Torres, Armando, Canaud, Guillaume, Legendre, C., Logt, Anne-Els,, Moulin, B., Ronco, Pierre, Logt, A. van de, Castan, J.A. Ballarín, Yousfi, Nadhir, Cruzado, J.M., Gandhi, M.J., Alexander, M.P., Rieu, Philippe, Logt, Anne-Els van de, Brenchley, Paul, Canaud, G., Moulin, Bruno, OndrejViklický, ., Choukroun, G., Wetzels, J., Letouzé, E., Yousfi, N., Moyer, Ann M, Berchtold, Lena, Dubois, Valérie, Gandhi, Manish, J, Moyer, A.M., Legendre, Christophe, Gandhi, Manish J, Moyer, Ann, M, Ballarín Castan, José Aurelio, Hamilton, Patrick, Vuiblet, V., Rieu, P., Levi, Charlène, Mousson, C., Hamilton, P., Torres, A. Cedillo, Maria Cruzado, Josep, Alexander, Mariam Priya   +66 more
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