Results 41 to 50 of about 12,711 (259)
PLoS ONE, 2023 Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy.
Omar Ragy +5 more
doaj +2 more sources
Rituximab in Membranous Nephropathy [PDF]
, 2021 Membranous nephropathy is the most common cause of primary nephrotic syndrome among adults. The identification of phospholipase A2 receptor (PLA2R) as target antigen in a majority of patients changed the management of membranous nephropathy dramatically,
Federico Alberici (4503547) +38 more
core
Rituximab Therapy for Primary Membranous Nephropathy in a Chinese Cohort [PDF]
Frontiers in Medicine, 2021 Background: Rituximab has become one of the first-line therapies for the treatment of moderate and high-risk primary membranous nephropathy (pMN). We retrospectively reviewed 95 patients with pMN who received rituximab therapy and focused on the therapeutic effects and safety of this therapy in a Chinese cohort.Methods: Ninety-five consecutive patients
Shuang Gao +40 more
openaire +3 more sources
Membranous Nephropathy: Current Understanding in The Light of New Advances [PDF]
, 2023 Membranous nephropathy is the most common cause of primary nephrotic syndrome in adults. The most important mech-anism in its pathogenesis is loss of immune tolerance.
Baloglu, Ismail +7 more
core +1 more source
SAGE Open Medical Case Reports, 2018 Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer +5 more
doaj +1 more source
Overlap of Primary Membranous Nephropathy, IgA Nephropathy, and Diabetic Nephropathy: A Case Report
Cureus, 2023 The coexistence of primary membranous nephropathy (PMN), immunoglobulin A nephropathy (IgAN), and diabetic nephropathy (DN) in the same patient has been a subject of clinical and pathological investigation, yielding inconclusive results. The limited availability of cases and resource materials has hindered a comprehensive understanding of this ...
openaire +2 more sources
BMC Nephrology, 2018 Background Despite the development of biomarkers and noninvasive imaging tools, biopsy remains the only method for correctly diagnosing patients with unexplained hematuria, proteinuria and renal failure.
Hsien-Fu Chiu +4 more
doaj +1 more source
Primary membranous glomerulonephritis-associated with schistosomal nephropathy
Indian Journal of Nephrology, 2019 The association of bilharziasis with membranous nephropathy (MN) has long been debated. The relatively recent use of antibodies against the M-type phospholipase A2 receptor (PLA2R) has been proposed as a valuable tool to discriminate the idiopathic from secondary MNs.
Mohammad Ibrahim, Walaa Hosny +3 more
openaire +2 more sources
Immune-Monitoring Disease Activity in Primary Membranous Nephropathy [PDF]
Frontiers in Medicine, 2019 Primary membranous nephropathy (MN) is a glomerular disease mediated by autoreactive antibodies, being the main cause of nephrotic syndrome among adult patients. While the pathogenesis of MN is still controversial, the detection of autoantibodies against two specific glomerular antigens, phospholipase A2 receptor (PLA2R) and thrombospondin type 1 ...
Paolo Cravedi +6 more
openaire +5 more sources
Clinical Phenotypes and Predictors of Remission in Primary Membranous Nephropathy [PDF]
Journal of Clinical Medicine, 2021 (1) Background: We sought to investigate the clinical outcome and to identify the independent predictors of clinical remission in a prospectively followed cohort of patients with primary membranous nephropathy (pMN). (2) Methods: We conducted a prospective, observational, non-interventional study that included 65 consecutive patients diagnosed with pMN
Roxana Jurubiță +6 more
openaire +2 more sources