Results 61 to 70 of about 376,168 (350)

Multisensory integration and motor resonance in the primary motor cortex

Cortex
Humans are endowed with a motor system that resonates to speech sounds, but whether concurrent visual information from lip movements can improve speech perception at a motor level through multisensory integration mechanisms remains unknown. Therefore, the aim of the study was to explore behavioral and neurophysiological correlates of multisensory ...
Serena Giurgola, Emanuele Lo Gerfo, Alessandro Farnè, Alice C. Roy, Nadia Bolognini   +4 more
openaire   +5 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Spatio-Temporal Patterning in Primary Motor Cortex at Movement Onset [PDF]

, 2017
Voluntary movement initiation involves the engagement of large populations of motor cortical neurons around movement onset. Despite knowledge of the temporal dynamics that lead to movement, the spatial structure of these dynamics across the cortical ...
Best, Matthew D., Brown, Kevin A., Hatsopoulos, Nicholas G., Suminski, Aaron J., Takahashi, Kazutaka   +4 more
core   +1 more source

Altered Modulation of Silent Period in Tongue Motor Cortex of Persistent Developmental Stuttering in Relation to Stuttering Severity [PDF]

, 2016
Motor balance in developmental stuttering (DS) was investigated with Transcranial Magnetic Stimulation (TMS), with the aim to define novel neural markers of persistent DS in adulthood. Eleven DS adult males were evaluated with TMS on tongue primary motor
Battaglini, Piero Paolo, Bencich, Marco, Bernardini, Simona, Busan, Pierpaolo, Del Ben, Giovanni, Manganotti, Paolo, Monti, Fabrizio, Natarelli, Giulia   +7 more
core   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Effects of Transcranial Direct Current Stimulation Over the Left Primary Motor Cortex on Verbal Intelligence

Frontiers in Human Neuroscience, 2022
Previous studies have shown that changes in gray matter density and volume in the left primary motor cortex are significantly associated with changes in individuals’ verbal intelligence quotient (VIQ), but not with their performance intelligence quotient
Yifan Huang, Yinling Zhang, Yizhe Zhang, Xiaoqin Mai   +3 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

fNIRS Study of Brain Activation during Multiple Motor Control Conditions in Younger and Older Adults

Journal of Integrative Neuroscience
Background: Evidence suggests that aging contributes to decreased cerebral blood flow and brain oxyhemoglobin (HbO2) in the association cortices during rest.
Duoduo Yu, Conghui Wei, Zhen Yuan, Jun Luo   +3 more
doaj   +1 more source

Dual-hemispheric transcranial direct current stimulation (tDCS) over primary motor cortex does not affect movement selection.

PLoS ONE, 2019
Volition and sense of agency are two primary components of a voluntary or internally generated movement. It has been shown that movement selection cannot be altered without interfering with the sense of volition using single pulse transcranial magnetic ...
Nivethida Thirugnanasambandam, Felix G Contreras-Castro, Mark Hallett   +2 more
doaj   +1 more source

Quantitative patterns of motor cortex proteinopathy across ALS genotypes

Acta Neuropathologica Communications, 2020
Degeneration of the primary motor cortex is a defining feature of amyotrophic lateral sclerosis (ALS), which is associated with the accumulation of microscopic protein aggregates in neurons and glia. However, little is known about the quantitative burden
Matthew Nolan, Connor Scott, Menuka Pallebage Gamarallage, Daniel Lunn, Kilda Carpenter, Elizabeth McDonough, Dan Meyer, Sireesha Kaanumalle, Alberto Santamaria-Pang, Martin R. Turner, Kevin Talbot, Olaf Ansorge   +11 more
doaj   +1 more source