Results 81 to 90 of about 376,168 (350)

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation. [PDF]

, 2016
Using ultra-high field 7 Tesla (7T) functional magnetic resonance imaging (fMRI), we map the cortical and perceptual responses elicited by intraneural microstimulation (INMS) of single mechanoreceptive afferent units in the median nerve, in humans ...
Ackerley, Benjamini, Benjamini, Besle, Bianciardi, Blankenburg, Burton, Burton, Favorov, Ferretti, Francis, Gati, Gelnar, Gescheider, Huang, Hurley, Johansson, Johansson, Kaas, Kampe, Kelly, Klatzky, Landry, Martuzzi, Masamoto, McGlone, Nelson, Ochoa, Overduin, Paul, Penfield, Preusser, Rausell, Reed, Sanchez-Panchuelo, Sanchez-Panchuelo, Servos, Tommerdahl, Torebjörk, Trulsson, Uğurbil, Vallbo, Vallbo, Vallbo, Vickery   +44 more
core   +5 more sources

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge, Roberto S. Hernandez, Nora C. Hernandez, Phyllis L. Faust, Elan D. Louis   +4 more
wiley   +1 more source

Structure-function abnormalities in cortical sensory projections in embouchure dystonia

NeuroImage: Clinical, 2020
Background: Embouchure dystonia (ED) is a task-specific focal dystonia in professional brass players leading to abnormal orofacial muscle posturing/spasms during performance.
Tobias Mantel, Eckart Altenmüller, Yong Li, André Lee, Tobias Meindl, Angela Jochim, Claus Zimmer, Bernhard Haslinger   +7 more
doaj   +1 more source

Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge. [PDF]

, 2019
The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation.
Baker, Dewleen G, Davis, Bryan, Huang, Charles, Huang, Mingxiong, Kimball, Donald, Lerman, Imanuel, Proudfoot, James, Rao, Ramesh, Simmons, Alan N, Simon, Bruce, Sorkin, Linda, Spadoni, Andrea, Strigo, Irina, Zhong, Edward   +13 more
core   +2 more sources

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

All Talk and No Action: A Transcranial Magnetic Stimulation Study of Motor Cortex Activation During Action Word Production [PDF]

, 2011
A number of researchers have proposed that the premotor and motor areas are critical for the representation of words that refer to actions, but not objects. Recent evidence against this hypothesis indicates that the left premotor cortex is more sensitive
Caramazza, Alfonso, Finocchiaro, Chiara, Gangitano, Massimo, Oliveri, Massimiliano, Pascual-Leone, Alvaro, Shapiro, Kevin Alfred   +5 more
core   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

What Disconnection Tells about Motor Imagery: Evidence from Paraplegic Patients [PDF]

, 2017
Brain activation during motor imagery has been the subject of a large number of studies in healthy subjects, leading to divergent interpretations with respect to the role of descending pathways and kinesthetic feedback on the mental rehearsal of ...
Alkadhi, Hatem, Boendermaker, Sabina Hotz, Brugger, Peter, Crelier, Gerard, Curt, Armin, Hepp-Reymond, Marie-Claude, Kollias, Spyros S.   +6 more
core  

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source