The object of this study was to verify motor cortex reorganization in patients with primary motor cortex injury using functional magnetic resonance imaging.Ten control subjects and two patients with primary motor cortex injury, caused by a traumatic brain injury in patient 1 and meningioma in patient 2, were evaluated.
Sung Ho Jang+5 more
openaire +4 more sources
Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study
ABSTRACT Objectives Considering the characteristics of multiple sclerosis (MS) disease and its impact on motor disability, this study aims to assess the functional integrity of the corticospinal tract by examining motor evoked potentials (MEPs), Expanded Disability Status Scale (EDSS) scores, magnetic resonance imaging (MRI) lesion counts, and ...
Antonia Bralić+13 more
wiley +1 more source
Detecting Resting-state Neural Connectivity Using Dynamic Network Analysis on Multiband fMRI Data [PDF]
This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were estimated at each voxel with respect to the sensory-motor network and default-mode network.
arxiv
Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy
ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling+6 more
wiley +1 more source
How transcranial direct current stimulation facilitates post-stroke rehabilitation [PDF]
Whether transcranial direct current stimulation (tDCS) benefits stroke rehabilitation remains unclear. To investigate how tDCS reorganizes brain circuitry, nineteen post-stroke patients underwent rehabilitation sessions with bi-hemispheric real vs sham tDCS intervention. Resting motor threshold measurements showed tDCS evoked higher excitability in the
arxiv
What is the functional relevance of reorganization in primary motor cortex after spinal cord injury?
Motor output maps within primary motor cortex are widely distributed and modified by motor skill learning and neurological injury. Functions that these maps represent after spinal cord injury remain debatable.
M.A. Urbin+4 more
doaj
HPDL Variant Type Correlates With Clinical Disease Onset and Severity
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee+19 more
wiley +1 more source
Involvement of Primary Motor Cortex in Motor Imagery: A Neuromagnetic Study
Functional brain imaging studies have indicated that several cortical and subcortical areas active during actual motor performance are also active during imagination or mental rehearsal of movements. Recent evidence shows that the primary motor cortex may also be involved in motor imagery.
Riitta Hari+4 more
openaire +2 more sources
CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu+12 more
wiley +1 more source
A Framework for Exploring Non-Linear Functional Connectivity and Causality in the Human Brain: Mutual Connectivity Analysis (MCA) of Resting-State Functional MRI with Convergent Cross-Mapping and Non-Metric Clustering [PDF]
We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure and exploring causality between network components.
arxiv