Results 231 to 240 of about 97,838 (263)
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Autoimmune primary ovarian insufficiency
Autoimmunity Reviews, 2014Primary ovarian insufficiency (POI) is defined as sustained amenorrhea, increased follicle-stimulating hormone and low estrogen levels, whereas diminished ovarian reserve (DOR) is characterized as regular menses and alterations of ovarian reserve tests.
C A, Silva +5 more
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Seminars in Reproductive Medicine, 2016
Primary ovarian insufficiency (POI), also known as premature ovarian failure or premature menopause, is defined as cessation of menstruation before the expected age of menopause. Potential etiologies for POI can be divided into genetic, autoimmune, and iatrogenic categories.
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Primary ovarian insufficiency (POI), also known as premature ovarian failure or premature menopause, is defined as cessation of menstruation before the expected age of menopause. Potential etiologies for POI can be divided into genetic, autoimmune, and iatrogenic categories.
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Journal of Reproductive Immunology, 2023
OBJECTIVE Stem cell/exosome therapy is a novel strategy for primary ovarian insufficiency (POI). This paper is to examine the role of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (hUCMSC-EVs) in POI. METHODS hUCMSC-EVs were
Yan Lu +7 more
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OBJECTIVE Stem cell/exosome therapy is a novel strategy for primary ovarian insufficiency (POI). This paper is to examine the role of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (hUCMSC-EVs) in POI. METHODS hUCMSC-EVs were
Yan Lu +7 more
semanticscholar +1 more source
Journal of Clinical Endocrinology and Metabolism, 2023
CONTEXT POI is a heterogeneous disease with an unknown underlying trigger or root cause. Recently many studies evaluated non-coding RNAs (ncRNAs), especially microRNAs (miRNAs), long non-coding RNA (lncRNAs), circular RNAs (circRNAs), and short ...
Jun-Hui Zhang +6 more
semanticscholar +1 more source
CONTEXT POI is a heterogeneous disease with an unknown underlying trigger or root cause. Recently many studies evaluated non-coding RNAs (ncRNAs), especially microRNAs (miRNAs), long non-coding RNA (lncRNAs), circular RNAs (circRNAs), and short ...
Jun-Hui Zhang +6 more
semanticscholar +1 more source
Genetics of Primary Ovarian Insufficiency
Clinical Obstetrics & Gynecology, 2020The diagnosis of primary ovarian insufficiency (POI) has untold effects on women and a better understanding alongside potential treatments are paramount to improve quality of life of these women. Various causes have been linked to the development of POI with genetics playing a key role.
Rukayat O, Akande, Yetunde, Ibrahim
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2017
Premature ovarian insufficiency (POI) can be defined as a cessation of ovarian function in women younger than 40 years old and is linked to the development of hypergonadotropic hypogonadism. The hypogonadism clinically presents as amenorrhea, which sometimes is preceded by oligomenorrhea and decreased circulating estradiol levels.
Agnieszka Podfigurna +4 more
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Premature ovarian insufficiency (POI) can be defined as a cessation of ovarian function in women younger than 40 years old and is linked to the development of hypergonadotropic hypogonadism. The hypogonadism clinically presents as amenorrhea, which sometimes is preceded by oligomenorrhea and decreased circulating estradiol levels.
Agnieszka Podfigurna +4 more
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Current Obstetrics and Gynecology Reports, 2014
Primary ovarian insufficiency (POI) is a syndrome of amenorrhoea, sex steroid deficiency, and elevated gonadotropins in a woman aged more than two standard deviations below the mean age for menopause estimated for her reference population. In practical terms, it occurs spontaneously in 1 % of women before the age of 40 years. Apart from idiopathic POI,
Rodney J. Baber, Michele Kwik
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Primary ovarian insufficiency (POI) is a syndrome of amenorrhoea, sex steroid deficiency, and elevated gonadotropins in a woman aged more than two standard deviations below the mean age for menopause estimated for her reference population. In practical terms, it occurs spontaneously in 1 % of women before the age of 40 years. Apart from idiopathic POI,
Rodney J. Baber, Michele Kwik
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Reproductive Biomedicine Online, 2023
RESEARCH QUESTION Is there a protective effect of the humanin derivative [Gly14]-humanin (HNG) on a D-gal-induced mouse model of primary ovarian insufficiency (POI), and what is the underlying mechanism?
Jin Huang +6 more
semanticscholar +1 more source
RESEARCH QUESTION Is there a protective effect of the humanin derivative [Gly14]-humanin (HNG) on a D-gal-induced mouse model of primary ovarian insufficiency (POI), and what is the underlying mechanism?
Jin Huang +6 more
semanticscholar +1 more source
Primary Ovarian Insufficiency: Current Concepts
Southern Medical Journal, 2017A potential consequence of chemotherapy is the destruction of oocytes, resulting in primary ovarian insufficiency (POI) in young patients; this often results in secondary amenorrhea and necessitates hormone replacement therapy. Regardless of the etiology of POI, the chance of pregnancy is low in this patient population. Given the extent to which oocyte
Gretchen, Collins +3 more
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Primary ovarian insufficiency: autoimmune causes
Current Opinion in Obstetrics & Gynecology, 2010To review the pathogenesis of premature ovarian insufficiency due to steroid cell autoimmunity (SCA-POI).Autoimmune oophoritis is characterized by a selective mononuclear cell infiltration into the theca layer of large, antral follicles, with earlier stage follicles consistently free of lymphocytic infiltration.
A. La Marca +5 more
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