Results 61 to 70 of about 1,621,791 (239)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Relationship Between Socioeconomic Status and Organized Sports Among Primary School Children: A Gender-Based Analysis of Sports Participation

Sports
Sports participation according to socioeconomic status (SES) was related to children in high-income Western countries. This study aimed to examine whether family or neighborhood-level SES is associated with current and continued organized sports ...
Chiaki Tanaka, Eun-Young Lee, Shigeho Tanaka   +2 more
doaj   +1 more source

Low food and nutrition literacy (FNLIT): a barrier to dietary diversity and nutrient adequacy in school age children

BMC Research Notes, 2020
Objective This study aims to assess the relationship between Food and Nutrition Literacy (FNLIT) and dietary diversity score (DDS); FNLIT and nutrient adequacy (NAR%, MAR%) in school-age children in Iran. Results This cross-sectional study was undertaken
Azam Doustmohammadian, Nasrin Omidvar, Nastaran Keshavarz-Mohammadi, Hassan Eini-Zinab, Maryam Amini, Morteza Abdollahi, Zeinab Amirhamidi, Homa Haidari   +7 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

School Feeding and Nutritional Status of Students in Dubti District, Afar, Northeast Ethiopia: Comparative Cross-Sectional Study

Pediatric Health, Medicine and Therapeutics, 2023
Kedir Hussein,1 Tefera Chanie Mekonnen,1 Foziya Mohammed Hussien,1 Tilahun Dessie Alene,2 Melese Shenkut Abebe3 1School of Public Health, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia; 2Department of Pediatrics, School of ...
Hussein K, Mekonnen TC, Hussien FM, Alene TD, Abebe MS   +4 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Influences of Training on Individual Outcomes for High School Sports Officials

SAGE Open, 2014
The primary purpose of this study was to explore the influences of training on specific quality of work outcomes of job satisfaction, pay satisfaction, and intentions to leave within high school sports officials.
Timothy D. Ryan, Jason P. Sosa, Michael A. Thornton   +2 more
doaj   +1 more source

KENYA PRIMARY SCHOOL TEACHERS’ PREPARATION IN ICT TEACHING: TEACHER BELIEFS, ATTITUDES, SELF-EFFICACY, COMPUTER COMPETENCE, AND AGE

African Journal of Teacher Education, 2017
Information and Communication Technologies (ICT) has become globally recognized as an effective medium for learning. The Kenyan government made a commitment to provide computers for use in teaching in primary schools.
Gladwell Njeri Wambiri, Mary Nyokabi Ndani   +1 more
doaj   +1 more source