Results 91 to 100 of about 429,268 (290)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Parents appointing the principal: The experiences of four New Zealand primary school boards of trustees [PDF]
, 2013 Universally motivated by altruism and the desire to serve their children’s schools well, locally elected parent representatives of New Zealand boards of trustees (BOTs) are charged with the responsibility of appointing the principal.
Morrison, Michele
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Citizen science projects related to Chemistry and Biology education: a systematic review
Frontiers in EducationIntroductionCitizen science is a participatory approach that enables the general population to collaborate in scientific research projects. In many cases, it is connected to Chemistry and Biology to address environmental, health, and educational ...
Carmen Viviana Basantes-Vaca +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Masculinities and primary schooling : two case studies [PDF]
This thesis is a study of the ways in which hegemonic masculinity is constructed in two primary schools. Its principal perspective is feminist, though it draws heavily on the substantial body of work on masculinities within sociology. Connell's (1987)
Skelton, Christine
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Social studies education in Nigeria: The challenge of building a nation [PDF]
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The general aim in conducting this research is to investigate the teaching and learning of Social Studies in Nigeria and to understand how it is taught and
Sofadekan, Adedayo Oyewole
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Validity of two general outcome measures of science and social studies achievement
Specialusis Ugdymas, 2016 The present research expanded validity findings for a structured formative assessment measure of content learning that was administered online and known as critical content monitoring.
Paul Mooney +3 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Secondary school students' attitudes to practical work in school science [PDF]
, 2012 Practical work is seen as having an important role in school science. In particular many have claimed that it has an essential role in determining students' attitudes to school science and science beyond the classroom. However, whilst there has been much
Sharpe, Rachael May, Sharpe, Rachael
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BMC Psychology, 2018 Background Wellbeing and resilience are essential in preventing and reducing the severity of mental health problems. Equipping children with coping skills and protective behavior can help them react positively to change and obstacles in life, allowing ...
Amanda Fenwick-Smith +2 more
doaj +1 more source