MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
An investigation into the experience of meeting the special educational needs of pupils in shift primary schools in Jamaica [PDF]
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.School days are organised on a whole day and or a shift basis in different countries.
Sherwood, Donna M
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ChildrenBackground/Objectives: Alcohol and tobacco use in adolescence are major public health concerns that shape long-term health trajectories and undermine healthy behaviour development.
Paula Concha-Gacitua +6 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Student voices: Experiences of Solomon Islands students in transition from primary school to boarding secondary school [PDF]
, 2010 This study is about students' experiences when in transition from primary schools they attended daily to boarding secondary schools located far from their homes and villages in the Solomon Islands.
Vasethe, Godfrey
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Children's daily travel to school in Johannesburg-Soweto, South Africa: geography and school choice in the Birth to Twenty cohort study [PDF]
, 2013 This paper has two aims: to explore approaches to the measurement of children’s daily travel to school in a context of limited geospatial data availability, and to provide data regarding school choice and distance travelled to school in Soweto ...
Julia de Kadt +10 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Factors affecting the choice of science subjects among girls at secondary level in Mauritius [PDF]
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research attempts to identify the factors which influence the choice of science subjects in Mauritius among girls at the end of the third year of ...
Naugah, Jayantee
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Current State of PhD Nursing Education in Four Countries: A Comparative Analysis
SAGE Open NursingIntroduction : The academic preparation of nurses is crucial to meet the needs of the global population. Doctoral education is imperative for nurses to conduct research and to develop evidence-based practices to ensure that nurses contribute to the ...
Thóra B. Hafsteinsdóttir RN, PhD +4 more
doaj +1 more source