Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Increasing women's participation in the primary school teaching force and teacher training in Nepal [PDF]
Although research shows that Nepalese parents prefer sending girls to schools with female teachers, only 12.8 percent of Nepalese primary school teachers are women. Nepal has among the lowest enrollment and retention rates for girls in the world.
Teas, Molly Maguire
core
Teaching Physical Education: Primary School Teachers as Learners [PDF]
This research focused on physical education (PE) teaching and learning in New Zealand primary school settings. The project had two key aims: first, to develop an understanding of the knowledges primary teachers use to teach PE, prior to a one-year ...
Petrie, Kirsten Culhane
core
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Education and Training in Montserrat:A Partially Annotated Bibliography [PDF]
This bibliography on “Education and Training in Montserrat” has been specifically prepared for the UWI School of Continuing Studies’ Montserrat Conference (2002).
Quamina-Aiyejina, Lynda
core
Socio-academic interventions in primary and lower secondary education: A scoping review
This scoping review highlights the intricate relationship between the social and academic dimensions of educational interventions. Spanning the subjects of mathematics, literacy and science in primary and lower secondary school (ages 5–15), the ...
Stine Thygesen +2 more
doaj +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Education and Training in St. Vincent and the Grenadines: A Partially Annotated Bibliography [PDF]
This bibliography on “Education and Training in St. Vincent and the Grenadines” has been specifically prepared for the UWI School of Continuing Studies’ St. Vincent and the Grenadines Conference.
Quamina-Aiyejina, Lynda
core
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source

