Results 51 to 60 of about 429,268 (290)
BJGP Open, 2023 Background: Different dementia support roles exist but evidence is lacking on which aspects are best, for whom, and in what circumstances, and on their associated costs and benefits.
Hannah Wheat +30 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Primary school teachers' understanding of themselves as professionals [PDF]
, 2013 This research study set out to gain an insight into primary school teachers’ understanding of themselves as professionals. The knowledge to be generated in this research is subjective as it involved teachers expressing their opinions and beliefs in the ...
O\u27Donovan, Bernadette +1 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Indonesian Journal of Science and Mathematics EducationTechnology-based learning is increasingly evolving in elementary education, including developing interactive media to enhance student learning outcomes. This study aimed to develop and evaluate the feasibility, practicality, and effectiveness of the Nature Ninja Edugame based on Articulate Storyline for the fifth-grade Natural and Social Sciences.
Fauza Cahya Paradisa, Ika Ratnaningrum
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Frontline Learning ResearchPrevious research suggests connections between peer relationships and children’s engagement and learning within the classroom. However few studies have explored these connections in detail or considered the possible processes that may begin to explain ...
Edward Baines +7 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Children's relationships with their physical school: Considerations of primary architecture and furniture design in a social and cultural context [PDF]
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University on behalf of Buckinghamshire New University.In recent years substantial investment has been made to replace or refurbish state schools in England and ...
Cullis, Robert Ian
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