Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The implementation and impact of the secondary science National Strategy: A single-school case study to explore the changes in classroom teaching styles and the responses of students to these initiatives [PDF]
This thesis was submitted for the degree of Doctor of Education and awarded by Brunel University, 7/10/2010.The National Strategy for Science was progressively introduced from 2002 with the intention of providing a clear structure for improved delivery ...
Lloyd-Staples, Chris
core
MODEL PENDIDIKAN KARAKTER TERINTEGRASI PADA PEMBELAJARAN DI PENDIDIKAN DASAR
This paper examines conceptually integrated character education related to basic education, both in general/Islamic elementary school. Character education includes a set of values which will be implemented on learning.
Muhamad Mustaqim
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A STUDY OF SINGAPORE FEMALE PRIMARY TEACHERS’ SELF-EFFICACY FOR TEACHING SCIENCE [PDF]
According to Bandura, self-efficacy is defined as an individual’s judgment of their capability to organize and execute the courses of action required to attain designated types of performances.
NG, WEE-LOON
core
Examining The Attitudes Of Primary School Students Towards Science and Social Studies Courses
The study aims to identify the fourth graders’ attitudes towards the courses of science and social studies and the correlations between them. The study was conducted with the participation of 285 fourth graders attending the primary schools in Mersin and Balıkesir in 2017-2018 academic year.
Şeker, Burcu Sezginsoy +1 more
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Embracing innovation and gaining ‘ownership’ of the social studies exemplars: A classroom based study [PDF]
This research supports the on-going national research that has accompanied the development and implementation of the New Zealand Ministry of Education's social studies curriculum exemplars (2004).
Ramsbottom, Rosamund
core
Protocol for a systematic review of the effects of schools and school-environment interventions on health: evidence mapping and syntheses. [PDF]
BACKGROUND: Schools may have important effects on students' and staff's health. Rather than treating schools merely as sites for health education, 'school-environment' interventions treat schools as settings which influence health.
Moore, L. +55 more
core +1 more source
Physical activity integration in elementary education seeks to promote academic performance and the physical, emotional and social health of students. This study aims to examine the effect of active methodologies involving physical activity in primary ...
Rafael Francisco Caracuel-Cáliz +3 more
doaj +1 more source

