Results 91 to 100 of about 323,453 (311)
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
DYNAMICS OF CONSTRUCTIVE BEHAVIOR FORMATION IN PRIMARY SCHOOL STUDENTS
This article is devoted to the dynamics of the formation of constructive behavior in primary school students. The article also covers primary school students' behavior, national upbringing, respect for adults, exemplary learning activities, compromise ...
Norkuzieva Dilrabo Sheralievna
core
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
FORMATION OF TEXT CREATION SKILLS IN PRIMARY SCHOOL STUDENTS
The article provides recommendations on the methods used by primary school students to solve problems in literacy and text ...
Ergasheva Shokhista Akmaljon qizi
core +1 more source
AbstractThis study aims to determine the suggestions of primary school teaching final year students in regard to the introduction of environmental consciousness. A quantitative research approach was adopted in the present study conducted with 73 students receiving education at the Department of Primary School Teaching at Kastamonu University Faculty of
Bozdemir, Hafife +2 more
openaire +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Prevalence of Programming Misconceptions in Primary School Students
ISBN:979-8-4007-1038 ...
Hartmann, Marco +2 more
openaire +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
OPPORTUNITIES FOR INDEPENDENCE IN PRIMARY SCHOOL STUDENTS
This article describes how to use and apply advanced methodological experience for independent thinking and research of primary school students. It is shown that the education of children's independence is carried out in a step-by-step manner.
Mahkamjonovna, Axmadalieva Muborakxon
core +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source

