Results 71 to 80 of about 323,043 (265)

Parasomnia in the Students of Primary Schools

open access: yesJournal of Holistic Nursing and Midwifery, 2014
Abstract Introduction: Parasomnia is circadian behaviors that occur to the people while they sleep. Repeating parasomnia could reduce quality and quantity of sleeping pattern. This sleeping disorder will refer to severe insomnia among children. Objective: The aim of this study is to find out parasomnia among primary schools student.
Zahra Shafi Pour   +3 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Primary School Teacher Candidates’ Offers to Primary School Students about Environmental Consciousness

open access: yesProcedia - Social and Behavioral Sciences, 2014
AbstractThis study aims to determine the suggestions of primary school teaching final year students in regard to the introduction of environmental consciousness. A quantitative research approach was adopted in the present study conducted with 73 students receiving education at the Department of Primary School Teaching at Kastamonu University Faculty of
Bozdemir, Hafife   +2 more
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Prevalence of dental caries among the primary and middle school students in a district of Hangzhou City, Zhejiang Province, in the 2020 school year

open access: yesShanghai yufang yixue
ObjectiveTo understand the prevalence of dental caries among the primary and middle school students in Yuhang District, Hangzhou City, in order to provide a basis for reducing the prevalence and preventing dental caries, as well as providing data support
FANG Hangyan, LEI Chao
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A study on prevalence of Pediculosis in the primary school students of Babol, 2003-04

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005
.
A Zabihi   +3 more
doaj  

Home - About - Disclaimer - Privacy