Results 151 to 160 of about 37,561 (261)

Single‐Cell and Spatial Omics: Methods and Applications

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Systematically summarized the breakthrough sequencing technologies and computational methods for single‐cell and spatial omics across multiple omics layers, including genome, epigenome, transcriptome, proteome, and metabolome. State‐of‐the‐art methods for multi‐omics integration, cross‐modal integration, and cross‐scale integration were reviewed, with ...
Xiaoping Cen   +10 more
wiley   +1 more source

Exploring the Intersection of Rare Diseases and Mental Health Within the Diagnostic Odyssey: A Narrative Review and Thematic Synthesis

open access: yesNursing Open, Volume 13, Issue 4, April 2026.
ABSTRACT Aim To explore what is known about the intersection of mental health and rare diseases. Design Narrative review with peer‐reviewed literature from 2009 onwards. Methods The study searched for literature on these databases in September 2024: CINAHL, Scopus, Pubmed, Medline, Embase, and PsycInfo, as well as citation chaining and supplementary ...
Eileen Wu, Sophie Isobel, Paul Beckett
wiley   +1 more source

Different Knots, Same Outcome: Evaluating the Role of Surgical Technique on Biliary Anastomotic Strictures After Liver Transplantation

open access: yesWorld Journal of Surgery, Volume 50, Issue 4, Page 1082-1089, April 2026.
Biliary anastomotic strictures (BAS) after liver transplant (LT) are a significant contributor to post‐transplant morbidity. Although surgical technique has been proposed as a risk factor, accurate evaluation of technique has been limited by inherent bias in conventional definitions for BAS.
Samith Minu Alwis   +7 more
wiley   +1 more source

Diabetes Mellitus is a Risk Factor for Hepatic Encephalopathy Following Transjugular Intrahepatic Portosystemic Shunt

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 7, Page 967-978, April 2026.
Diabetes mellitus independently increases the risk of hepatic encephalopathy following TIPS placement in patients with cirrhosis. These findings emphasize the need for careful risk assessment in patients with cirrhosis and portal hypertension complications undergoing TIPS.
Michelle Spaan   +16 more
wiley   +1 more source

Primary Sclerosing Cholangitis: Diagnosis, Management, and Clinical Challenges. [PDF]

open access: yesJ Clin Med
Svensson Di Giorgio S   +4 more
europepmc   +1 more source

Characterisation and Prognostic Implication of Cholestasis After Burn Injury

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 8, Page 1140-1150, April 2026.
In 532 burn ICU patients, we quantified trajectories of cholestasis markers and validated burn‐associated cholestasis definitions. Bilirubin dynamics, particularly hyperbilirubinemia ≥ 2× ULN within 14 days, independently predicted excess in‐hospital and overall mortality beyond burn and critical‐illness severity, identifying a high‐risk subgroup after
Lorenz Semmler   +16 more
wiley   +1 more source

Feasibility of Early Oral Nutritional Supplementation After Liver Transplantation: A Randomized Pilot Study

open access: yesClinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT Catabolic and inflammatory changes after liver transplantation (LT) increase energy and protein requirements. This study assessed the feasibility of a 12‐week high‐energy/high‐protein oral nutrition supplementation (ONS) initiated after resumption of solid oral intake post‐LT.
Amal Trigui   +7 more
wiley   +1 more source

MUC1 as a biomarker in primary sclerosing cholangitis and cholangiocarcinoma. [PDF]

open access: yesAnn Gastroenterol
Hashash JG   +7 more
europepmc   +1 more source

Rhesus Antagonism Is Associated With Non‐Anastomotic Biliary Strictures After Orthotopic Liver Transplantation From Brain‐Death Donors

open access: yesClinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT Background Biliary non‐anastomotic strictures (NAS) are among the most severe complications of liver transplantation (LT). Risk factors include donation after circulatory death (DCD) as compared to donation after brain death (DBD) and prolonged ischemia times.
Leonard D. (Niels) Broekman   +5 more
wiley   +1 more source

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