Results 31 to 40 of about 278,937 (311)

MicroRNA-214 modulates neural progenitor cell differentiation by targeting Quaking during cerebral cortex development

open access: yesScientific Reports, 2017
The accurate generation of an appropriate number of different neuronal and glial subtypes is fundamental to normal brain functions and requires tightly orchestrated spatial and temporal developmental programmes to maintain the balance between the ...
Pengcheng Shu   +13 more
doaj   +1 more source

A comparative analysis of play behaviour in primates and carnivores [PDF]

open access: yes, 2003
This thesis considers the evolution of play behaviour, focusing on comparative analyses of extant primates and carnivores from various perspectives, including intra-specific analyses, life-history, socio-ecology, and brain anatomy, taking data from the ...
Lewis, Kerrie Patricia
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

The Internal, External and Extended Microbiomes of Hominins

open access: yesFrontiers in Ecology and Evolution, 2020
The social structure of primates has recently been shown to influence the composition of their microbiomes. What is less clear is how primate microbiomes might in turn influence their social behavior, either in general or with particular reference to ...
Robert R. Dunn   +6 more
doaj   +1 more source

A generalizable brain extraction net (BEN) for multimodal MRI data from rodents, nonhuman primates, and humans

open access: yeseLife, 2022
Accurate brain tissue extraction on magnetic resonance imaging (MRI) data is crucial for analyzing brain structure and function. While several conventional tools have been optimized to handle human brain data, there have been no generalizable methods to ...
Ziqi Yu   +8 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Road Infrastructure and Primate Conservation: Introducing the Global Primate Roadkill Database

open access: yesAnimals, 2023
As road infrastructure networks rapidly expand globally, especially in the tropics, previously continuous habitats are being fragmented, resulting in more frequent wildlife–vehicle collisions (WVC).
Laura C. Praill   +18 more
doaj   +1 more source

Culture in Non-human Primates: Definitions and Evidence [PDF]

open access: yes, 2013
The attribution of culture to non-human animals has been controversial and continues to fuel much heated debate, much of which hinges on how culture is defined.
Newton-Fisher, Nicholas E.   +1 more
core  

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang   +13 more
wiley   +1 more source

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