Results 101 to 110 of about 995,884 (279)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Relative Prime Coprime Graph of Integers Modulo Group and Its Reverse Topological Indices
Pan-American Journal of MathematicsThe relationship between edges and vertices is fundamental to graph theory, significantly influencing different graph properties and applications.
Abdurahim - +3 more
doaj +1 more source
Revue Internationale du Marketing et Management Stratégique, 2023 L’instauration d’un système de prime au rendement des enseignants présente un défi théorique et pratique. Quelles sont alors les opportunités de la mise en œuvre d’un tel système au secteur de l’éducation? Par quels moyens évaluer ce rendement?
ACHNID JAOUAD, OUKASSI MUSTAPHA
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A New Characterization of Projective Special Unitary Groups PSU3(3n)
Discussiones Mathematicae - General Algebra and Applications, 2019 One of an important problems in finite groups theory, is characterization of groups by specific property. However, in the way the researchers, proved that some of groups by properties such as, elements order, set of elements with same order, graphs, . . .
Ebrahimzadeh Behnam, Mohammadyari Reza
doaj +1 more source
The prime element theorem in additive arithmetic semigroups. I
Illinois Journal of Mathematics, 1996 The author continues his investigations on prime element theorems in additive semigroups which he started in part I [Ill. J. Math. 40, 245-280 (1996; Zbl 0863.11065)]. The main purpose is to prove stronger estimates of the remainder terms, i.e. instead of \(o(1)\)-type now more explicitly some \(O(1)\)-type.
openaire +5 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Properties of ϕ-Primal Graded Ideals
Journal of Mathematics, 2017 Let R be a commutative graded ring with unity 1≠0. A proper graded ideal of R is a graded ideal I of R such that I≠R. Let ϕ:I(R)→I(R)∪{∅} be any function, where I(R) denotes the set of all proper graded ideals of R.
Ameer Jaber
doaj +1 more source