Results 61 to 70 of about 58,364 (303)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

$0$-ideals in $0$-distributive posets [PDF]

Mathematica Bohemica, 2016
The concept of a $0$-ideal in $0$-distributive posets is introduced. Several properties of $0$-ideals in $0$-distributive posets are established. Further, the interrelationships between $0$-ideals and $\alpha$-ideals in $0$-distributive posets are ...
Khalid A. Mokbel
doaj   +1 more source

Prime ideal theorem for double Boolean algebras [PDF]

, 2007
Double Boolean algebras are algebras (D,⊓,⊔,⊲,⊳,⊥,⊤) of type (2,2,1,1,0,0). They have been introduced to capture the equational theory of the algebra of protoconcepts. A filter (resp. an ideal) of a double Boolean algebra D is an upper set F (resp.
Kwuida, Léonard
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The hull-kernel topology on prime ideals in ordered semigroups

Open Mathematics
The aim of this study is to develop the theory of prime ideals in ordered semigroups. First, to ensure the existence of prime ideals, we study a class of ordered semigroups which will be denoted by SIP{{\mathbb{S}}}_{IP}.
Wu Huanrong, Zhang Huarong
doaj   +1 more source

On Rough Fuzzy Prime Ideals in Left Almost Semigroups

International Journal of Analysis and Applications, 2021
In this paper we shall introduce the notion of rough prime ideals and rough fuzzy prime ideals in LA-semigroups. We proved that the lower and the upper approximation of a prime ideal is a prime ideal and we also proved that a fuzzy subset f of an LA ...
Ahmed Elmoasry
doaj  

Ideals as generalized prime ideal factorization of submodules [PDF]

, 2023
For a submodule $N$ of an $R$-module $M$, a unique product of prime ideals in $R$ is assigned, which is called the generalized prime ideal factorization of $N$ in $M$, and denoted as ${\mathcal{P}}_M(N)$. But for a product of prime ideals ${{{\mathfrak{p}
Duraivel, T., Mangayarcarassy, S., Thulasi, K. R.   +2 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Intuitionistic fuzzy weakly prime ideals [PDF]

Journal of Hyperstructures, 2017
In this study, the fundamental definitions and theorems regarding intuitionistic fuzzy sets and intuitionistic fuzzy ideals of commutative ring R with identity have been given as preliminaries.
Tu˘gba Arkan, Serkan Onar, Deniz S¨onmez, Bayram Ersoy   +3 more
doaj   +1 more source