Results 81 to 90 of about 730,391 (289)

On the Frohman Kania-Bartoszynska ideal

open access: yes, 2004
The Frohman Kania-Bartoszynska ideal is an invariant associated to a 3-manifold with boundary and a prime p >3. We give some estimates of this ideal.
Gilmer, Patrick M.
core   +4 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

On Soft Near-Prime Int-Ideals and Soft 1-Absorbing Prime Int-Ideals With Applications

open access: yesJournal of Mathematics
In this study, we aimed to introduce two different generalizations of the soft prime int-ideal and clarify the relationships between the soft prime int-ideal and the substructures of a ring. First, we explored new algebraic features of the soft prime int-
İbrahim Halil Kanat, Filiz Çıtak
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Disjunctive Ideals of Almost Distributive Lattices

open access: yesDiscussiones Mathematicae - General Algebra and Applications, 2022
The concept of disjunctive ideals is introduced in an Almost Distributive Lattice (ADL). It is proved that the set of all disjunctive ideals of an ADL forms a complete lattice.
Rafi N., Srujana M., Rao T. Srinivasa
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A note on the Eisenbud-Mazur Conjecture [PDF]

open access: yes, 2014
The Eisenbud-Mazur conjecture states that given an equicharacteristic zero, regular local ring (R,\mathfrak{m}) and a prime ideal P\subset R, we have that P^{(2)}\subseteq mP.
More, Ajinkya A
core  

Valuation domains whose products of free modules are separable

open access: yes, 2007
It is proved that if $R$ is a valuation domain with maximal ideal $P$ and if $R_L$ is countably generated for each prime ideal $L$, then $R^R$ is separable if and only $R_J$ is maximal, where $J=\cap_{n\in\mathbb{N}}P^n$
Couchot, Francois
core   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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