Results 101 to 110 of about 11,551,305 (305)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Holographic realization of the prime number quantum potential. [PDF]
PNAS Nexus, 2023 Cassettari D, Mussardo G, Trombettoni A.
europepmc +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The number of rational points of some classes of algebraic varieties over finite fields
Open MathematicsLet Fq{{\mathbb{F}}}_{q} be the finite field of characteristic pp and Fq*=Fq\{0}{{\mathbb{F}}}_{q}^{* }\left={{\mathbb{F}}}_{q}\backslash \left\{0\right\}.
Zhu Guangyan +3 more
doaj +1 more source
On a Fractal Representation of the Density of Primes
Recoletos Multidisciplinary Research Journal, 2014 The number of primes less or equal to a real number x, π(x), has been approximated in the past by the reciprocal of the logarithm of the number x. Such an approximation works well when x is large but it can be poor when x is small.
Joy Mirasol, Efren O. Barabat
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Weighted Prime Number Theorem on Arithmetic Progressions with Refinements
MathematicsWe present an extension of the Dirichlet-type prime number theorem to weighted counting functions, the importance of which has recently been recognized for formulating Chebyshev’s bias.
Koji Shimada, Shin-ya Koyama
doaj +1 more source
A FORMULA FOR THE n-TH PRIME NUMBER
, 2013 A new formula for the n-th prime number is introduced. It is based on an arithmetic function, similar to the operation “differentiation”, but defined only over natural numbers.
K. Atanassov
semanticscholar +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source