Results 91 to 100 of about 11,551,305 (305)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Subsets of prime numbers received by means of generalized arithmetic progression
Дифференциальная геометрия многообразий фигур, 2018 A short historical information about formulas and polynomials generating subsets of prime numbers is given. Examples of subsets of prime numbers by using generalized arithmetic progression are obtained.
V. Malakhovsky
doaj
Open MathematicsIn the context of a simple undirected graph GG, a kk-prime labeling refers to assigning distinct integers from the set {k,k+1,…,∣V(G)∣+k−1}\left\{k,k+1,\ldots ,| V\left(G)| +k-1\right\} to its vertices, such that adjacent vertices in GG are labeled with ...
Abughneim Omar A., Abughazaleh Baha’
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Distribution of the prime numbers
Bulletin of Applied Mathematics and Mathematics EducationThis research explores the distribution of prime numbers, which are a fundamental topic in number theory. The study originated from the author's fascination with mathematics and the desire to discover something novel.
Lolav Ahmed Khalil
semanticscholar +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Multiscale Sieve for Smart Prime Generation and Application in Info-Security, IoT and Blockchain
Applied SciencesThe huge computational cost required to test whether a number is prime and the inefficiency of the known sieving algorithms for extremely large inputs have posed significant challenges in computational number theory.
Gerardo Iovane +2 more
doaj +1 more source
Formula for primes, twinprimes, number of primes and number of twinprimes [PDF]
Proceedings Mathematical Sciences, 1983 Assuming that the first n primes are known the author gives a formula for calculating \(p_{n+1}\), the \((n+1)st\) prime. Formulas are also given for the smallest twin prime (if any) in the interval \((p_ n,p^ 2_ n)\) and for both the number of primes and twin primes not exceeding x if x is between \(p_ n\) and \(p^ 2_ n\).
openaire +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source