Results 41 to 50 of about 143,448 (228)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Investigating Schema-Free Encoding of Categorical Data Using Prime Numbers in a Geospatial Context

open access: yesISPRS International Journal of Geo-Information, 2019
Prime numbers are routinely used in a variety of applications, e.g., cryptography and hashing. A prime number can only be divided by one and the number itself.
Martin Sudmanns
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

About finding of prime numbers that follow after given prime number without using computer

open access: yesДифференциальная геометрия многообразий фигур, 2020
It is shown how to define one or several prime numbers following af­ter given prime number without using computer only by calculating sev­eral arithmetic progressions. Five examples of finding such prime num­bers are given.
V.S. Malakhovsky
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Scale Invariant Distribution of the Prime Numbers

open access: yesComputation, 2015
The irregular distribution of prime numbers amongst the integers has found multiple uses, from engineering applications of cryptography to quantum theory.
Wayne S. Kendal, Bent Jørgensen
doaj   +1 more source

Some Observations on the Greatest Prime Factor of an Integer

open access: yesAnnales Mathematicae Silesianae, 2023
We examine the multiplicity of the greatest prime factor in k-full numbers and k-free numbers. We generalize a well-known result on greatest prime factors and obtain formulas related with the Riemann zeta function.
Jakimczuk Rafael
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

On some characteristics of subset of prime numbers

open access: yesДифференциальная геометрия многообразий фигур, 2019
The set of prime numbers p ≥ 5 is divided into two nonoverlapping subset P1 = {6k1 - 1}, P2 = {6k2 + 1}, where ki ⋲ A (i = 1,2). Subsets A1, A2 of natural numbers is defined by differences Ai = N\Bi, where B1, B2 are subset {j1}, {j2} defining subsets ...
V. Malakhovsky
doaj   +1 more source

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