Results 51 to 60 of about 147,553 (263)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Investigating Schema-Free Encoding of Categorical Data Using Prime Numbers in a Geospatial Context
Prime numbers are routinely used in a variety of applications, e.g., cryptography and hashing. A prime number can only be divided by one and the number itself.
Martin Sudmanns
doaj +1 more source
Prime and prime power divisibility of Catalan numbers
AbstractFor any prime p, the sequence of Catalan numbers an=1n2n−2n−1 is divided by the an prime to p into blocks Bk(k > 0) of an divisible by p. The lengths and positions of the Bk are determined. Additional results are obtained on prime power divisibility of Catalan numbers.
Ronald Alter, K. K. Kubota
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
About finding of prime numbers that follow after given prime number without using computer
It is shown how to define one or several prime numbers following after given prime number without using computer only by calculating several arithmetic progressions. Five examples of finding such prime numbers are given.
V.S. Malakhovsky
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Scale Invariant Distribution of the Prime Numbers
The irregular distribution of prime numbers amongst the integers has found multiple uses, from engineering applications of cryptography to quantum theory.
Wayne S. Kendal, Bent Jørgensen
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On some characteristics of subset of prime numbers
The set of prime numbers p ≥ 5 is divided into two nonoverlapping subset P1 = {6k1 - 1}, P2 = {6k2 + 1}, where ki ⋲ A (i = 1,2). Subsets A1, A2 of natural numbers is defined by differences Ai = N\Bi, where B1, B2 are subset {j1}, {j2} defining subsets ...
V. Malakhovsky
doaj +1 more source

