Results 41 to 50 of about 78,445 (293)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
PRIMARY ZARISKI TOPOLOGY ON THE PRIMARY SPECTRUM OF A MODULE [PDF]
Journal of Algebraic Systems, 2020 Let $R$ be a commutative ring with identity and let $M$ be an $R$-module. We define the primary spectrum of $M$, denoted by $\mathcal{PS}(M)$, to be the set of all primary submodules $Q$ of $M$ such that $(\operatorname{rad}Q:M)=\sqrt{(Q:M ...
H. Bijari +2 more
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A New Approach to Spread-spectrum OFDM
, 2018 Orthogonal frequency division multiplexing (OFDM) systems are reviewed and the Shannon bound is dis- cussed as a criterion of efficient spectrum use and a design criterion. The problem of efficient sharing of spectrum by wireless communication systems is
Shahab Abdulla +5 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On some aspects of the generalized Petersen graph
Electronic Journal of Graph Theory and Applications, 2017 Let $p \ge 3$ be a positive integer and let $k \in {1, 2, ..., p-1} \ \lfloor p/2 \rfloor$. The generalized Petersen graph GP(p,k) has its vertex and edge set as $V(GP(p, k)) = \{u_i : i \in Zp\} \cup \{u_i^\prime : i \in Z_p\}$ and $E(GP(p, k)) = \{u_i ...
V. Yegnanarayanan
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Methyl 5′-Chloro-8-formyl-5-hydroxy-1′,3′,3′-trimethyl-spiro-[chromene-2,2′-indoline]-6-carboxylate
, 2023 Spiropyrans modified with reactive polyfunctional substituents are of great interest as building blocks for the creation of various smart systems with controllable properties for materials science and biomedicine.
Boris S. Lukyanov +8 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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Congruence Extensions in Congruence–Modular Varieties
AxiomsWe investigate from an algebraic and topological point of view the minimal prime spectrum of a universal algebra, considering the prime congruences with respect to the term condition commutator.
George Georgescu +2 more
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Applied Sciences, 2021 In fields such as biology, archeology, and industry, underwater photogrammetry can be achieved using consumer-grade equipment. However, camera operations underwater differ considerably from those on land because underwater photogrammetry involves ...
Chun-Feng Chou +9 more
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