Results 221 to 230 of about 618,007 (340)

Rewiring Dendritic Cell Immunity: The β-Catenin-TIM-3 Axis as a Target to Improve DC Cancer Vaccines. [PDF]

Cancers (Basel)
Fu C, Ma T, Zhou L, Mi QS, Jiang A.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Immune Revolution: A Case for Priming, Not Checkpoint.

Cancer Cell, 2018
R. Vonderheide
semanticscholar   +1 more source

Trained immunity and immune priming in plants and invertebrates. [PDF]

Elife
Kurtz J, Andino R, Boraschi D, Contreras-Garduño J, Kachroo A, Khan I, Lanz Mendoza H, Mukherjee K, Peuß R, Ton J.   +9 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Reframing adjuvant immunotherapy in melanoma: all of it starts with priming. [PDF]

J Immunother Cancer
Ascierto PA, Melero I.
europepmc   +1 more source

Cross-priming [PDF]

Nature Immunology, 2006
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rhizosphere priming effect: A meta-analysis

, 2017
C. Huo, Yiqi Luo, W. Cheng
semanticscholar   +1 more source

Priming for enhanced defense.

Annual Review of Phytopathology, 2015
U. Conrath, G. Beckers, C. Langenbach, Michal Jaskiewicz   +3 more
semanticscholar   +1 more source