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Primordial germ cell migration
International Journal of Developmental Biology, 2004 Mutational and antisense screens in Drosophila and zebrafish, and transcriptional profiling and time-lapse analysis in the mouse, have contributed greatly to our understanding of PGC development. In all three systems, the behavior of PGCs is controlled by growth factors which signal through G-protein coupled receptors and/or tyrosine kinase receptors ...
Christopher Wylie, Wylie Christopher
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From primordial germ cell to primordial follicle: mammalian female germ cell development
Genesis, 2006In mammals, the final number of oocytes available for reproduction of the next generation is defined at birth. Establishment of this oocyte pool is essential for fertility. Mammalian primordial germ cells form and migrate to the gonad during embryonic development. After arriving at the gonad, the germ cells are called oogonia and develop in clusters of
Melissa Pepling
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Primordial Germ Cells and Fecundity
Nature, 1966THE origin of the definitive germ cells of vertebrates from the primordial germ cells of the embryonic period is now widely accepted and has been supported in the case of a few species1–4 by quantitative observations, which make it unnecessary to postulate the neo-formation of germ cells from the somatic elements of the so-called ‘germinal epithelium’.
M W, Hardisty, J, Cosh
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2017
Germ cells transmit genetic information to the next generation through gametogenesis. Primordial germ cells (PGCs) are the first germ-cell population established during development, and are the common origins of both oocytes and spermatogonia. Unlike in other species, PGCs in birds undergo blood circulation to migrate toward the genital ridge, and are ...
Takahiro, Tagami +2 more
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Germ cells transmit genetic information to the next generation through gametogenesis. Primordial germ cells (PGCs) are the first germ-cell population established during development, and are the common origins of both oocytes and spermatogonia. Unlike in other species, PGCs in birds undergo blood circulation to migrate toward the genital ridge, and are ...
Takahiro, Tagami +2 more
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The Biology of Primordial Germ Cells
European Urology, 1993Primordial germ cells are the founder cells of the gametes. They arise at the earliest stages of development, and migrate to the genital ridges, where they join the somatic cells of the future gonad. The factors that determine their formation and migration are largely unknown.
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The induction of the primordial germ cells in the urodeles
Wilhelm Roux' Archiv f�r Entwicklungsmechanik der Organismen, 1974Xenoplastic recombinates of animal ectodermal caps with the ventral vegetative yolk mass of blastulae of stage 81/2-83/4 ofA. mexicanum, T. alpestris, T. cristatus carnifex andP. waltlii have demonstrated unambiguously that in the urodeles the primordial germ cells-together with other ventro-caudal mesodermal structures-develop from the animal ...
Lien A, Sutasurja, P D, Nieuwkoop
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Isolation of mouse primordial germ cells
Experimental Cell Research, 1982Abstract Primordial germ cells (PGCs) were obtained from fetal mouse gonads of both sexes 12 1 2 and 13 1 2 days post coitum (dpc), either by collagenase treatment, or by mechanical procedures with or without prior EDTA treatment.
DE FELICI, MASSIMO, McLaren, A.
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The mechanical journey of primordial germ cells
American Journal of Physiology-Cell PhysiologyPrimordial germ cells (PGCs) are the earliest progenitors of germline cells of the gonads in animals. The tissues that arise from primordial germ cells give rise to male and female gametes and are thus responsible for transmitting genetic information to subsequent generations.
Malhar S. Chitnis +3 more
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Development of primordial germ cells in the mouse*
Andrologia, 2009Primordial germ cells in the mouse are known to be derived from the epiblast. They can be identified histochemically, by their high alkaline phosphatase activity. At 8 d post coitum they have been observed within the embryonic part of the egg cylinder, at the posterior end of the primitive streak.
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Primordial Germ Cells and Germ Line Stem Cells
2015Germ cells are a sexual reproductive cell type at any stage from primordial germ cells (PGCs) to mature gametes. Germ line stem cells are important for genetic transmission to future generations. In this review, we focus on female germ line stem cells (FGSCs), spermatogonial stem cells (SSCs), and PGCs.
Ji Wu +5 more
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