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Reprogramming Primordial Germ Cells (PGC) to Embryonic Germ (EG) Cells
Current Protocols in Stem Cell Biology, 2008AbstractIn this unit we describe the derivation of pluripotent embryonic germ (EG) cells from mouse primordial germ cells (PGCs) isolated from both 8.5‐ and 11.5‐days post‐coitum (dpc) embryos. Once EG cells are derived we explain how to propagate and characterize the cell lines.
Gabriela, Durcova-Hills, Azim, Surani
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On the Migration of the Primordial Germ Cells
1974Rather surprisingly, we find in many vertebrates and invertebrates that the primordial germ cells, from which eggs and sperm are later derived by division and differentiation, are initially not located in the mesodermal gonad primordium. In many vertebrates they are first visible within the endoderm. This means that the primordial germ cells often must
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Primordial Germ Cells in Mammals
1995Germ cells, defined as cells all of whose surviving descendants give rise to gametes (eggs or sperm), are the most fascinating cells in the body. The germ cell lineage, or germline, provides the only biological link, the only route of genetic transmission, from one generation to the next.
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[Ontogenesis of primordial germ cells].
Medecine sciences : M/S, 2005In sexually reproducing animals all gametes of either sex arise from primordial germ cells (PGC). PGC represent a small cell population, appearing early during embryo development. They represent a key cell population responsible for the survival and the evolution of a species.
Nadejda, Machev +2 more
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Two Novel lncRNAs Regulate Primordial Germ Cell Development in Zebrafish
Cells, 2023, Yi Meisheng, Jian-Fang Gui
exaly
Primordial germ cell migration.
Ciba Foundation symposium, 1995Primordial germ cells are migratory cells. They arise very early in embryogenesis and have a similar pattern of migration in Drosophila, Xenopus, chick and mouse. In each case the primordial germ cells associate with the developing gut from which they migrate to the gonads during organogenesis.
M, Gomperts, C, Wylie, J, Heasman
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A transitory signaling center controls timing of primordial germ cell differentiation
Developmental Cell, 2021Ruth Lehmann +2 more
exaly