Results 81 to 90 of about 9,239,414 (293)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
PRINCIPAL LEADERSHIP STYLE AND ITS EFFECT ON TEACHERS PERFORMANCE
Jurnal Aplikasi Manajemen, 2019 This study aims to analyze the effect of the application of leadership style on the teacher’s performance and the dominant leadership style on the teacher’s performance.
Elpisah Elpisah, Hartini Hartini
doaj +1 more source
Simplicial Nonlinear Principal Component Analysis [PDF]
, 2012 We present a new manifold learning algorithm that takes a set of data points lying on or near a lower dimensional manifold as input, possibly with noise, and outputs a simplicial complex that fits the data and the manifold.
Hunt, Thomas, Krener, Arthur J.
core +1 more source
Functional Decomposition using Principal Subfields
, 2017 Let $f\in K(t)$ be a univariate rational function. It is well known that any non-trivial decomposition $g \circ h$, with $g,h\in K(t)$, corresponds to a non-trivial subfield $K(f(t))\subsetneq L \subsetneq K(t)$ and vice-versa.
Allem, Luiz E. +3 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
, 2016 We revisit the problem of finding principal components to the multivariate datasets, that lie on an embedded nonlinear Riemannian manifold within the higher-dimensional space.
Pham, Tung, Yao, Zhigang
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2016 The purpose of this study was to: (1) describe the leadership style of the principal in improving teacher performance; (2) describe the role of the school principal; (3) describe the factor endowments and a barrier in improving the performance of ...
Wahyu Ramadoni +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source