Results 101 to 110 of about 2,140,628 (292)

Globally convergent method for designing twice spline contractual function

open access: yesJournal of Inequalities and Applications, 2019
To design a quadratic spline contractual function in the case of discretely unknown nodes, a modified constraint shifting homotopy algorithm for solving principal–agent problems is constructed in the paper.
Zhichuan Zhu   +2 more
doaj   +1 more source

The Crowding-Out of Work Ethics [PDF]

open access: yes
This paper analyses optimal contracts in a principal-agent model where the agent is intrinsically motivated at the outset and there is an endogenous relationship between the structure of incentive payments and intrinsic motivation (crowding effects). The
Grepperud, Sverre   +1 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

On the Determination and Use of Principal Lines

open access: yesEngineering Transactions, 1977
Assuming plane strain for Huber-Mises yield condition (for a Coulomb-Tresca one, both plane strain and stress are admitted) of incompressible homogeneous isotropic ideal plastic medium, basic relation of principal lines (of curvatures and their ...
M. Rogoziński
doaj  

Multidimensional Investigation of the Effect of Pre-treatment Solutions on Drying Characteristics and Raisin Quality

open access: yesJournal of Agricultural Sciences
This study aims to evaluate the relationships between pre-treatment solution, variety, drying characteristics, and raisin quality in raisin production, using multivariate analysis methods.
Cuneyt Uyak, Şahin Yılmaz
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Elastic–plastic criterion solution of deep roadway surrounding rock based on intermediate principal stress and Drucker–Prager criterion

open access: yesEnergy Science & Engineering
Excavation‐induced rock failure and deformation near an underground opening boundary is closely associated with the intermediate principal stress, strain softening and rock mass dilation.
Xinfeng Wang   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Analisis Kemampuan Manajerial Kepala Sekolah Dalam Implementasi Pembelajaran Daring

open access: yesScholaria: Jurnal Pendidikan dan Kebudayaan, 2021
The Covid-19 pandemic has a major impact, especially on education in elementary schools, so that the managerial skills of school principals are needed in implementing online learning in schools.
Afif Tri Hastowo, Muhammad Abduh
doaj  

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