Results 41 to 50 of about 1,382,324 (319)

The Double Traveling Salesman Problem with Multiple Stacks and a Choice of Container Types

open access: yesMathematics, 2020
The double traveling salesman problem with multiple stacks involves the transportation of goods between two regions. In one region, a vehicle carrying a container visits customers, where pallets of goods are loaded into the container.
Lars Magnus Hvattum   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The Disobeying 'Soldier': Use of an Achiral Group to Modulate Chiral Induction in PNA Duplexes

open access: yesCHIMIA, 2018
Peptide nucleic acid (PNA) is a synthetic analogue of DNA in which the natural nucleobases A, G, C, and T are linked to an achiral, charge neutral, pseudopeptide backbone.
Artur Sargun   +2 more
doaj   +1 more source

Proposal for an Optical Test of the Einstein Equivalence Principle

open access: yes, 2019
The Einstein Equivalence Principle (EEP) underpins all metric theories of gravity. Its key element is the local position invariance of non-gravitational experiments, which entails the gravitational red-shift.
Magnani, Piergiovanni   +6 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Energy Consumption Analysis of Frozen Sandy Soil and an Improved Double Yield Surface Elastoplastic Model considering the Particle Breakage

open access: yesAdvances in Civil Engineering, 2019
The stress-strain relationship of frozen soil is a hot research topic in the field of frozen soil mechanics. In order to study the effect of particle crushing on the stress-strain relationship, a series of triaxial compression tests for frozen sandy soil
Junlin He   +4 more
doaj   +1 more source

Investigation of an Output Voltage Harmonic Suppression Strategy of a Power Quality Control Device for the High-End Manufacturing Industry

open access: yesMicromachines, 2022
Due to the influence of nonlinear loads, power quality control devices under the traditional double closed-loop control strategy suffer from a large output voltage harmonic distortion rate and a slow harmonic suppression response and cannot meet the high-
Chengkuan Wan   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Principle of Double Effect within Catholic Moral Theology: A Response to Two Criticisms of the Principle in Relation to Palliative Sedation

open access: yesJournal of Moral Theology, 2017
If not considered an isolated principle but as part of Catholic moral theology, the principle of double can serve as an aid to discernment of the morality of an action, as one moral principle in the context of a broader moral system.
Gina Maria Noia
doaj  

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