Results 141 to 150 of about 10,379,704 (316)
Gerstmann-Sträussler-Scheinker disease revisited: accumulation of covalently-linked multimers of internal prion protein fragments [PDF]
, 2019 Despite their phenotypic heterogeneity, most human prion diseases belong to two broadly defined groups: Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS).
Cali, Ignazio +8 more
core +1 more source
Reverse zoonosis of the 2022–2023 human seasonal H3N2 detected in swine
npj VirusesThe Iowa State University Veterinary Diagnostic Laboratory detected nineteen human-to-swine reverse zoonoses of the 2022–2023 human seasonal H3N2 between November 2022 and November 2023. Cases from seven U.S.
Michael A. Zeller +6 more
doaj +1 more source
Glia, 2014 The expansion of the microglial population is one of the hallmarks of numerous brain disorders. The addition of circulating progenitors to the pool of brain macrophages can contribute to the progression of brain disease and needs to be precisely defined ...
Diego G Omez-Nicola +3 more
semanticscholar +1 more source
Brain Pathology, EarlyView.A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
Transcriptional profile of Glaesserella parasuis in swine serosal and joint fluids
Frontiers in Veterinary ScienceGlaesserella parasuis is the causative agent of Glässer's disease and contributes to significant post-weaning mortality in the swine industry. Glässer's disease is characterized by meningitis, polyserositis, and polyarthritis.
Daniel W. Nielsen +3 more
doaj +1 more source
BOLL‐Containing Aggregates Mediate the Translational Regulation During Human Oogenesis
Cell Proliferation, EarlyView.This work elucidates that BOLL‐containing aggregate‐mediated translational control is essential for human oogenesis. These aggregates recruit PABPC1 and FXR1 to activate the translation of U‐rich mRNAs encoding cell cycle proteins, thereby ensuring successful meiotic progression.
Ying Li +5 more
wiley +1 more source
Prions and Prion Diseases [PDF]
Laboratory Medicine, 1999 Prion diseases (transmissible encephalopathies) are progressive neurodegenerative diseases of animals and humans caused by a unique agent, the prion. These diseases have recently been in the news because of the emergence of bovine spongiform encephalopathy (BSE; mad cow disease) and variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom.
openaire +1 more source
Assessment of land‐based threats to Atlantic pelagic seabirds
Conservation Science and Practice, EarlyView.Highly mobile pelagic seabirds face numerous land‐based threats during their breeding seasons, including invasive alien species, climate change, and diseases, which drive population declines. Using field expertise and a literature review, we collated a dataset assessing 18 threats affecting 49 species across 38 Atlantic Large Marine Ecosystems. We used
Ioannis Kalaitzakis +38 more
wiley +1 more source
Targeting of the prion protein to the cytosol: mechanisms and consequences
, 2010 Prion diseases are characterized by the conformational transition of the cellular prion protein (PrPC) into an aberrant protein conformer, designated scrapie-prion protein (PrPSc).
Miesbauer, M. +3 more
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