Results 271 to 280 of about 10,379,704 (316)
Some of the next articles are maybe not open access.
Clinics in Laboratory Medicine, 2010
Prion diseases are disorders affecting the central nervous system caused by alterations in the conformation of the cellular prion protein. They can be sporadic, hereditary, or acquired and usually present with myoclonus and rapidly progressive dementia in human patients.
openaire +2 more sources
Prion diseases are disorders affecting the central nervous system caused by alterations in the conformation of the cellular prion protein. They can be sporadic, hereditary, or acquired and usually present with myoclonus and rapidly progressive dementia in human patients.
openaire +2 more sources
Current Opinion in Infectious Diseases, 2019
Purpose of review Prion diseases are rapidly progressive neurodegenerative conditions that can be difficult to diagnose and are transmissible under specific circumstances. The authors will provide background regarding prion disease and focus on diagnostic tools.
Han, Wang +2 more
openaire +2 more sources
Purpose of review Prion diseases are rapidly progressive neurodegenerative conditions that can be difficult to diagnose and are transmissible under specific circumstances. The authors will provide background regarding prion disease and focus on diagnostic tools.
Han, Wang +2 more
openaire +2 more sources
Current Opinion in Neurology, 1997
Prion diseases are a group of disorders sharing clinical and pathological features. Many of the enigmas of these diseases have now yielded to the concerted effort to understand them and their unusual pathogenesis. The genetic backgrounds of the various diseases are being clarified at an impressive rate, but the cause of sporadic Creutzfeldt-Jakob ...
openaire +2 more sources
Prion diseases are a group of disorders sharing clinical and pathological features. Many of the enigmas of these diseases have now yielded to the concerted effort to understand them and their unusual pathogenesis. The genetic backgrounds of the various diseases are being clarified at an impressive rate, but the cause of sporadic Creutzfeldt-Jakob ...
openaire +2 more sources
Annals of Neurology, 1994
AbstractThe prion diseases, sometimes referred to as the “transmissible spongiform encephalopathies,” include kuru, Creutzfeldt‐Jakob disease, and Gerstmann‐Sträussler‐Scheinker disease of humans as well as scrapie and bovine spongiform encephalopathy of animals. For many years, the prion diseases were thought to be caused by viruses despite intriguing
S B, Prusiner, K K, Hsiao
openaire +2 more sources
AbstractThe prion diseases, sometimes referred to as the “transmissible spongiform encephalopathies,” include kuru, Creutzfeldt‐Jakob disease, and Gerstmann‐Sträussler‐Scheinker disease of humans as well as scrapie and bovine spongiform encephalopathy of animals. For many years, the prion diseases were thought to be caused by viruses despite intriguing
S B, Prusiner, K K, Hsiao
openaire +2 more sources
2017
Prion diseases are a group of invariably fatal and transmissible neurodegenerative disorders that are associated with the misfolding of the normal cellular prion protein, with the misfolded conformers constituting an infectious unit referred to as a "prion".
Benjamin C, Whitechurch +3 more
openaire +2 more sources
Prion diseases are a group of invariably fatal and transmissible neurodegenerative disorders that are associated with the misfolding of the normal cellular prion protein, with the misfolded conformers constituting an infectious unit referred to as a "prion".
Benjamin C, Whitechurch +3 more
openaire +2 more sources
Seminars in Neurology, 2000
The prion diseases constitute an unusual group of neurodegenerative disorders. Although they are similar in many ways to other more common diseases, such as Alzheimer disease and amyotrophic lateral sclerosis, they are set apart on the basis of their transmissible nature.
J A, Mastrianni, R P, Roos
openaire +2 more sources
The prion diseases constitute an unusual group of neurodegenerative disorders. Although they are similar in many ways to other more common diseases, such as Alzheimer disease and amyotrophic lateral sclerosis, they are set apart on the basis of their transmissible nature.
J A, Mastrianni, R P, Roos
openaire +2 more sources
Current Opinion in Neurology, 1995
Major advances have been made in prion diseases. Recent data indicate that the prion protein is likely to be a synaptic protein with a functional role in synaptic transmission. An impressive body of evidence suggests that (1) the normal prion protein plays a central role in prion replication; (2) the replication process implies an interaction between ...
P, Parchi, P, Gambetti
openaire +2 more sources
Major advances have been made in prion diseases. Recent data indicate that the prion protein is likely to be a synaptic protein with a functional role in synaptic transmission. An impressive body of evidence suggests that (1) the normal prion protein plays a central role in prion replication; (2) the replication process implies an interaction between ...
P, Parchi, P, Gambetti
openaire +2 more sources
Medical Clinics of North America, 2002
Transmissible spongiform encephalopathy (TSE) is a group of rare, sub-acute, fatal neurodegenerative diseases in humans and animals. TSE includes Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Scheinker disease, fatal familial insomnia, and Kuru (a disease confined to the Fore linguistic group, a tribe in Papua-New Guinea).
Man-Sun, Sy +2 more
openaire +2 more sources
Transmissible spongiform encephalopathy (TSE) is a group of rare, sub-acute, fatal neurodegenerative diseases in humans and animals. TSE includes Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Scheinker disease, fatal familial insomnia, and Kuru (a disease confined to the Fore linguistic group, a tribe in Papua-New Guinea).
Man-Sun, Sy +2 more
openaire +2 more sources
2012
Prion diseases occur in many animal species, most notably in ruminants. While scrapie in sheep has been recognised for three centuries and goat scrapie has been recognised for decades, BSE in cattle is a relatively novel disease which was first diagnosed in the UK in the mid 1980s.
Otto, Windl, Mike, Dawson
openaire +2 more sources
Prion diseases occur in many animal species, most notably in ruminants. While scrapie in sheep has been recognised for three centuries and goat scrapie has been recognised for decades, BSE in cattle is a relatively novel disease which was first diagnosed in the UK in the mid 1980s.
Otto, Windl, Mike, Dawson
openaire +2 more sources
Therapeutische Umschau, 1999
Das Interesse an den Prionkrankheiten und speziell an der häufigsten menschlichen Form, der Creutzfeldt-Jakob Krankheit (CJD), ist zur Zeit aus zwei Gründen groß: 1) Die Bevölkerung möchte begreiflicherweise wissen, ob der Konsum von Rindfleisch eine CJD verursachen kann.
openaire +2 more sources
Das Interesse an den Prionkrankheiten und speziell an der häufigsten menschlichen Form, der Creutzfeldt-Jakob Krankheit (CJD), ist zur Zeit aus zwei Gründen groß: 1) Die Bevölkerung möchte begreiflicherweise wissen, ob der Konsum von Rindfleisch eine CJD verursachen kann.
openaire +2 more sources