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Prion diseases

European Neuropsychopharmacology, 2022
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Prions and Prion Diseases

2014
Prions are generally regarded as the most reliable markers of so-called prion diseases. With the advent of the protein-only concept of the transmission of prion diseases, which is predicated on the idea that prions are the infectious agents causing prion disease, and with the 1997 Nobel Prize for Medicine awarded for the prion protein concept, prions ...
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Human Prion Diseases

1996
Abstract Human prion diseases include idiopathic, genetic, and acquired disorders. Heterogeneous clinicopathologic features make diagnosis challenging. Accurate diagnosis requires a combined clinical, neuropathologic, genetic, and biochemical approach. Neuropathologic assessment is performed following autopsy in most cases.
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Neuroinflammation in Prion Disease

International Journal of Molecular Sciences, 2021
Caihong Zhu, Zhu Caihong
exaly  

Prions and prion diseases.

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 1997
Currently known transmissive spongiform encephalopathies in humans and animals are presented. Caused by prions, they are known as "prion disease". The results of extensive investigations of prions are described, as well as the theories about their nature.
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[The prion hypothesis and the human prion diseases].

Berliner und Munchener tierarztliche Wochenschrift, 2002
Our understanding of the pathogenesis of the transmissible spongiform encephalopathies (TSE) has made terrific headway over the past 40 years and some scientists are even of the opinion that this group of diseases belongs to the neurodegenerative syndromes best understood. On the other hand, the investigation of TSE has led to a multitude of unexpected
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Conformational conversion and prion disease

Nature Reviews Molecular Cell Biology, 2011
Liang Shen   +2 more
exaly  

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

Nucleic Acids Research, 2020
Eric Vallabh Minikel   +2 more
exaly  

Conformational conversion and prion disease: authors' reply

Nature Reviews Molecular Cell Biology, 2011
Mick F Tuite   +2 more
exaly  

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