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The term 'prion diseases' refers to a group of neurodegenerative disorders thought to be caused by prions, pathogenic agents with novel modes of replication and transmission. Prion diseases are characterized by long incubation periods ranging from months to years and are invariably fatal once clinical symptoms have appeared.
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A prion is a small infectious particle, which resist inactivation by procedures that modify nucleic acids. Transmissible spongiform encephalopathies (TSEs also known as prion diseases) are a group of progressive conditions that affects the brain and nervous system of humans and animals and are transmitted by prions.
Obi, R K, Nwanebu, F C
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The ESCRT Pathway's Role in Prion Diseases and Beyond. [PDF]
Taha HB.
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Vaccines for prion diseases: a realistic goal? [PDF]
Napper S, Schatzl HM.
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Potential Therapeutic Use of Stem Cells for Prion Diseases. [PDF]
Zayed M, Kook SH, Jeong BH.
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A Theoretical Framework on the Biology of Prion Diseases. [PDF]
Ramosaço E, Bajrami N, Vyshka G.
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Transmission Ratio Distortion in Genetic Prion Diseases: Clarifying Methodological Considerations. [PDF]
Kortazar-Zubizarreta I +4 more
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Geographic Diversity in the Incidence of Human Prion Diseases - China, 2006-2019. [PDF]
Shi Q +7 more
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