CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.Plasma biomarkers in CJD reveal multisystem involvement, with neuronal injury markers showing strong discriminative performance and vascular proteins indicating blood–brain barrier dysfunction. In asymptomatic PRNP mutation carriers, biomarker changes are minimal and emerge mainly near disease onset ABSTRACT Background Plasma markers of neuronal injury
Zhong‐Yun Chen +11 more
wiley +1 more source
Redox mechanisms and their pathological role in prion diseases: The road to ruin. [PDF]
PLoS Pathog, 2023 Spiers JG, Chen HC, Steinert JR.
europepmc +1 more source
Glia, Volume 74, Issue 1, January 2026.TDP‐43Q331K mice exhibit altered proliferative dynamics in oligodendrocytes and their precursors. Oligodendroglial cell death is evident in TDP‐43Q331K mice. TDP‐43Q331K mice display altered myelin reflectance and pathology in the spinal cord. ABSTRACT Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the ...
Katherine N. Lewis +8 more
wiley +1 more source
Collaborative strategies for wildlife health: case studies from the Canadian North
The Journal of Wildlife Management, Volume 90, Issue 1, January 2026.The integration of Indigenous perspectives with a One Health approach enables culturally relevant and sustainable zoonotic disease management and surveillance, as demonstrated through 4 case studies that highlight how empowering communities and facilitating inclusive, respectful, and collaborative governance across diverse sectors and knowledge systems
Cody J. Malone +8 more
wiley +1 more source
Development of a user guide to support administration of the MRC Prion Disease Rating Scale in research and clinical settings for prion diseases. [PDF]
PrionPulido RS +10 more
europepmc +1 more source
Role of CD40 in prion disease and the immune response to recombinant PrP
, 2013 Richard Rubenstein +3 more
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Locus coeruleus alterations in dementia with Lewy bodies: A systematic review
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.Abstract INTRODUCTION The locus coeruleus (LC) is a small nucleus located deep within the brainstem, serving as the brain's main source of noradrenergic neurons. Through its extensive projections, it plays a critical role in regulating cognitive processes and arousal.
Anaëlle Bain +5 more
wiley +1 more source
Therapeutic perspectives for prion diseases in humans and animals. [PDF]
PLoS PathogBenavente R, Morales R.
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Palliative Care Resource Utilization in Patients With Prion Disease
Roaa Zayat +4 more
openalex +2 more sources
A Fluorescent Oligothiophene-Bis-Triazine ligand interacts with PrP fibrils and detects SDS-resistant oligomers in human prion diseases [PDF]
, 2016 Thibaut Imberdis +8 more
openalex +1 more source