Results 181 to 190 of about 45,606 (277)

Ferroptosis-related mechanisms in prion diseases provide insights into neurodegeneration and reveal therapeutic implications. [PDF]

Redox Biol
Zayed M, Tayara H, Jeong BH.
europepmc   +1 more source

Creutzfeldt‐Jakob‐Like Presentation in Anti‐AMPAR Encephalitis

Annals of Neurology, Volume 99, Issue 6, Page 1466-1467, June 2026.
Kate Durbano, Marie Belley, Delphine Leclercq, Louis Cousyn   +3 more
wiley   +1 more source

Beyond the Known and Established Neurodegenerative Effects: Roles of APOE Across a Wide Spectrum of Pathophysiological Condition

MedComm, Volume 7, Issue 6, June 2026.
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina, Samantha Maurotti, Alberto Castagna, Tiziana Montalcini, Arturo Pujia, Luca Tirinato   +5 more
wiley   +1 more source

Presymptomatic pharmacological inhibition of mGluR5 improves survival in a mouse model of prion diseases. [PDF]

Acta Neuropathol Commun
Wang Y, Mohammadi B, Hartmann C, Hartmann K, Thies E, Matamoros-Angles A, Fang C, Harris DA, Tatzelt J, Altmeppen HC, Sepulveda-Falla D, Strittmatter SM, Glatzel M, Krasemann S.   +13 more
europepmc   +1 more source

A Theoretical Framework on the Biology of Prion Diseases. [PDF]

Acta Inform Med, 2023
Ramosaço E, Bajrami N, Vyshka G.
europepmc   +1 more source

Prion and Prion Diseases

, 2020
This review article provides the main information regarding a specific category of infectious diseases of animals and humans, the so-called transmissible spongiform encephalopathies, or prion infections. In a brief introduction explains the need for lighting issues in relation to environmental, veterinary public health importance in traffic and the ...
openaire   +1 more source

Investigating the structural basis of surfactant protein D oligomerization: The crucial role of Cys15‐Cys15/Cys20‐Cys20 disulfide bond linkage

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Surfactant protein D (SP‐D) plays a vital role in innate immunity by recognizing and binding to glycans on the surfaces of various pathogens. The oligomerization of SP‐D into dodecameric structures enhances its pathogen‐binding and antiviral activities.
Deng Li, Mona S. Minkara
wiley   +1 more source

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is characterized by the intracellular aggregation of the microtubule‐associated protein Tau. While the presence of large, insoluble neurofibrillary tangles has long been the primary focus of this research, a paradigm shift in the field now highlights smaller, soluble oligomers as the more neurotoxic Tau species leading
Joshua T. Skrehot, Dmitry Kurouski
wiley   +1 more source

Geographic Diversity in the Incidence of Human Prion Diseases - China, 2006-2019. [PDF]

China CDC Wkly, 2023
Shi Q, Xiao K, Gao L, Wu Y, Zhou W, Liang D, Chen C, Dong X.   +7 more
europepmc   +1 more source

Endoscopic Ultrasonography‐Guided Gastroenterostomy Is More Cost Effective Than Surgical Gastrojejunostomy: A Health‐Economic Evaluation Alongside a Randomized Trial

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background There is a paucity of data on the cost‐utility of endoscopic ultrasonography‐guided gastroenterostomy (EUS‐GE) compared with surgical gastrojejunostomy (SGJ) as palliative treatment of malignant gastric outlet obstruction. Methods In the ENDURO trial, 98 patients with malignant gastric outlet obstruction from 12 Dutch hospitals were
Yorick L. van de Pavert, Kirsten Opmeer, Marc G. Besselink, Rina Bijlsma, Dieke C. Booij, Jurjen J. Boonstra, Judith Boot, Marco J. Bruno, Olivier R. Busch, Freek Daams, Wouter J. M. Derksen, Paul Fockens, Janine B. Kastelijn, Bas Groot Koerkamp, Jeroen Hagendoorn, Jeanin E. van Hooft, Akin Inderson, Willem J. Lammers, Daan J. Lips, J. Sven D. Mieog, I. Quintus Molenaar, Alexander A. F. A. Veenhof, Niels G. Venneman, Robert C. Verdonk, Rogier P. Voermans, Roy L. J. van Wanrooij, Paco M. J. Welsing, Thomas R. de Wijkerslooth, Hjalmar C. van Santvoort, Leon M. G. Moons, Miriam P. van der Meulen, Frank P. Vleggaar, for the Dutch Pancreatic Cancer Group   +32 more
wiley   +1 more source