Results 191 to 200 of about 45,606 (277)

Prion Diseases-When Proteins Turn Lethal: Creutzfeldt-Jakob Disease (CJD) and the Quest for Classification, Diagnosis, Therapeutic Approaches, and Emerging Research. [PDF]

Molecules
Ramesh TS, Bartusik-Aebisher D, Dynarowicz K, Aebisher D.   +3 more
europepmc   +1 more source

Mimicking the Ocean: Critical Challenges in Scaffold Design and Tissue Texturization for Cell‐Cultured Seafood

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Cellular aquaculture offers a sustainable solution to global seafood demand, yet the production of high‐value, whole‐cut fillets is hindered by the “texture gap,” the inability to replicate the complex, anisotropic architecture of native fish muscle and its collagenous myosepta.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Enhanced Sensitivity of a Modified Quaking-Induced Conversion Diagnostic Test for the Broad Detection of Sporadic and Inherited Prion Diseases: A Retrospective Study. [PDF]

Ann Neurol
Myskiw J, Fox R, Kielich DMS, Lamoureux L, Leonhardt M, Nykvist O, Slota JA, Avery K, Phillipson C, Frost K, Simon S, Appleby BS, Bailey-Elkin BA, Booth SA.   +13 more
europepmc   +1 more source

Etiology matters: genetic and acquired prion diseases engage different mechanisms at a presymptomatic stage. [PDF]

Neural Regen Res, 2023
Jackson WS.
europepmc   +1 more source

RORA Targeting PRNP Modulates Age‐Related Cataract via Activation Oxidative Injury‐Induced Cellular Senescence and Apoptosis of Lens Epithelial Cells

Aging Cell, Volume 25, Issue 6, June 2026.
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou, Wanqian Li, Jiaojiao Zhang, Chao Cen, Wanqiu Zheng, Ruonan Li, Hong Cheng, Liang Liang, Juan Kang, Wenjuan Wan, Ke Hu, Shijie Zheng   +11 more
wiley   +1 more source

The Evolution of Experimental Rodent Models for Prion Diseases. [PDF]

J Neurochem
DeFranco JP, Telling GC.
europepmc   +1 more source

Early Diagnostic Measures to Confirm the Diagnosis of Human Prion Diseases. [PDF]

Cureus, 2023
Desai N, Purzycki T.
europepmc   +1 more source

Active Chlorine Antiseptics in Wound Care: Recent Advances and Perspectives for Military Medicine

APMIS, Volume 134, Issue 6, June 2026.
ABSTRACT The spread of multidrug‐resistant microorganisms remains a major global challenge that continues to worsen. Modern military conflicts intensify this problem by forcing healthcare systems to manage large numbers of patients with complex, heavily contaminated injuries in resource‐limited settings.
Bohdan Murashevych, Dmytro Stepanskyi, William M. Wuest, Tim Holm Jakobsen   +3 more
wiley   +1 more source

D178N prion protein mutation endows RML prions with new strain properties that do not mimic human genetic prion diseases. [PDF]

Acta Neuropathol
Masone A, Grasso A, Comerio L, Bruno R, Lavigna G, Vanni I, D'Agostino C, Orrù CD, Caughey B, Altmeppen HC, Castilla J, Giaccone G, Tagliavini F, Di Bari MA, Nonno R, Chiesa R.   +15 more
europepmc   +1 more source

Redox mechanisms and their pathological role in prion diseases: The road to ruin. [PDF]

PLoS Pathog, 2023
Spiers JG, Chen HC, Steinert JR.
europepmc   +1 more source