Results 171 to 180 of about 45,606 (277)

The octapeptide repeats of prion protein play critical roles in the pathogenesis of prion diseases. [PDF]

Acta Neuropathol Commun
Zhang X, Zhang J, Zhang Y, Wang D, Liu G, Wang M, Li C, Shi Q, Dong X, Yuan C, Li W, Ma J.   +11 more
europepmc   +1 more source

The ESCRT Pathway's Role in Prion Diseases and Beyond. [PDF]

J Neurosci, 2023
Taha HB.
europepmc   +1 more source

Networks of Indirect Contact Promote Spread of an Environmentally Transmitted Pathogen in a Highly Social Species

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Using behavioral observations and network simulations, we evaluate direct and indirect transmission of the MTBC pathogen M. mungi in banded mongooses. Incorporating intergroup scent marking reveals that environmentally mediated, socially directed pathways can promote spread at low transmissibility, elevating population prevalence even when direct ...
Jack R. Leitch, Neil R. Jordan, John M. Drake, Michael A. Cant, Kathleen A. Alexander   +4 more
wiley   +1 more source

Palliative care symptoms of people living with rapidly progressive prion diseases: a systematic review. [PDF]

BMC Palliat Care
Williams RT, White N, Kearns J, McNiven K, Marasigan AR, Sampson EL, Evans CJ, Mead S, Kupeli N, EMBED‐Care Programme.   +9 more
europepmc   +1 more source

Virgin Coconut Oil Attenuates Diabetic Kidney Disease via Gut Microbiota‐Metabolism‐Inflammation Axis Modulation in Type 2 Diabetic Mice

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study elucidates the multi‐targeted mechanisms of Virgin Coconut Oil (CO) as a dietary intervention for ameliorating Diabetic Kidney Disease (DKD). High‐purity medium‐chain fatty acids (MCFAs, primarily octanoic acid [C8:0] and decanoic acid [C10:0]) in CO significantly remodel the gut microbiota by enriching short‐chain fatty acid (SCFA ...
Keke Shao, Yun Cao, Ruiqi Gao, Xueyun Dong, Xuehui Liu, Hao Xu, Yunhan Xie, Linlin Xu, Jiayuan He, Min Chen, Leilei Zhang, Asmaa Ali, Liang Wu, Pingping Wang   +13 more
wiley   +1 more source

Transmission Ratio Distortion in Genetic Prion Diseases: Clarifying Methodological Considerations. [PDF]

Eur J Neurol
Kortazar-Zubizarreta I, Manero-Azua A, Eraña H, Castilla J, Perez de Nanclares G.   +4 more
europepmc   +1 more source

The Effect of Protein Tagging on Aggregation and Phase Separation

Journal of Cellular Biochemistry, Volume 127, Issue 6, June 2026.
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley   +1 more source

The Risk of Transmission of Genetic Prion Diseases is Greater Than 50. [PDF]

Eur J Neurol
Kortazar-Zubizarreta I, Manero-Azua A, Eraña H, Aguire U, Castilla J, Perez de Nanclares G.   +5 more
europepmc   +1 more source

Vaccines for prion diseases: a realistic goal? [PDF]

Cell Tissue Res, 2023
Napper S, Schatzl HM.
europepmc   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source