Results 161 to 170 of about 2,165,687 (231)

Vaccines for prion diseases: a realistic goal? [PDF]

Cell Tissue Res, 2023
Napper S, Schatzl HM.
europepmc   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

The role of complement in synaptic degeneration

, 2012
Synapse loss is an early event of many neurodegenerative diseases including Alzheimer?s disease and Parkinson?s disease. The causes and mechanisms that underpin synapse dysfunction and degeneration are poorly understood.
Malfa, Katya
core  

Palliative care symptoms of people living with rapidly progressive prion diseases: a systematic review. [PDF]

BMC Palliat Care
Williams RT, White N, Kearns J, McNiven K, Marasigan AR, Sampson EL, Evans CJ, Mead S, Kupeli N, EMBED‐Care Programme.   +9 more
europepmc   +1 more source

Spatiotemporal Progression Patterns of Striatal Dopamine Depletion and Cerebral Hypoperfusion in Parkinson's Disease

Movement Disorders, Volume 41, Issue 9, Page 2408-2421, September 2026.
Abstract Background The identification of Parkinson's disease (PD) subtypes is crucial for predicting the disease course and designing personalized therapeutic strategies. Objectives The aim of the study was to characterize the heterogeneity of the spatiotemporal evolutionary patterns of striatal dopamine depletion and cerebral hypoperfusion in PD ...
Yeeun Sun, Youngseok Choi, Chan Wook Park, Han Kyu Na, Hye Sun Lee, Yun Joong Kim, Young H. Sohn, Phil Hyu Lee, Jeyeon Lee, Seok Jong Chung   +9 more
wiley   +1 more source

Ferroptosis-related mechanisms in prion diseases provide insights into neurodegeneration and reveal therapeutic implications. [PDF]

Redox Biol
Zayed M, Tayara H, Jeong BH.
europepmc   +1 more source

A Theoretical Framework on the Biology of Prion Diseases. [PDF]

Acta Inform Med, 2023
Ramosaço E, Bajrami N, Vyshka G.
europepmc   +1 more source

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease

Neuroprotection, Volume 4, Issue 3, Page 262-274, September 2026.
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji, Liujia Lu, Kaidong Chen, Ruixuan Zhang, Yao Lu, Yachen Shi, Xiangming Fang   +6 more
wiley   +1 more source

Presymptomatic pharmacological inhibition of mGluR5 improves survival in a mouse model of prion diseases. [PDF]

Acta Neuropathol Commun
Wang Y, Mohammadi B, Hartmann C, Hartmann K, Thies E, Matamoros-Angles A, Fang C, Harris DA, Tatzelt J, Altmeppen HC, Sepulveda-Falla D, Strittmatter SM, Glatzel M, Krasemann S.   +13 more
europepmc   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, Volume 15, Issue 3, Page 176-193, September 2026.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source