Results 141 to 150 of about 3,400,014 (272)
Tropical farmers try to adapt calf‐rearing systems to temperate dairy industry standards. Calves in tick‐infested areas develop stronger immunity to TBD under controlled exposure to ticks. Early tick exposure promotes sustainable management, balancing tick infestation and developing TBD immunity.
Daniela Balseca +11 more
wiley +1 more source
Mammalian prions are composed of misfolded aggregated prion protein (PrP) with amyloid-like features. Prions are zoonotic disease agents that infect a wide variety of mammalian species including humans.
Nyström, Sofie,, Hammarström, Per,
core +1 more source
Long‐term stability of horizontal bone augmentation at implant sites
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu +3 more
wiley +1 more source
Potential health benefits of cold‐water immersion: the central role of PGC‐1α
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer +2 more
wiley +1 more source
Characterisation of cytosolic prion protein-mediated putative cytotoxicity in neuronal cell lines [PDF]
Prion diseases are a complex group of fatal neurodegenerative disorders with a broad host spectrum, which are characterised by strong neuronal cell loss, spongiform vacuolation and astrocytic proliferation.
Mehlhase, Jana
core
Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease
Hyperphosphorylation of the microtubule-associated protein tau is a significant determinant in AD (Alzheimer's disease), where it is associated with disrupted axonal transport and probably causes synaptic dysfunction.
Perry, V. Hugh +2 more
core +1 more source
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires +15 more
wiley +1 more source
Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber +24 more
wiley +1 more source
CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions
CX3CR1 deficiency promotes microglial migration toward CNS injury. Proteomic profiling reveals altered RHO‐mediated cytoskeletal signaling, while in vivo two‐photon imaging demonstrates increased process extension, velocity, and accumulation of Cx3cr1‐deficient microglia at lesion sites. ABSTRACT Microglia are innate immune cells of the central nervous
Jens Wagner +13 more
wiley +1 more source
Microplastics and nanoplastics (MPs/NPs) are emerging environmental neurotoxicants capable of accumulating in the human brain through blood‐brain barrier transcytosis and olfactory transport pathways. Once within the central nervous system, MPs/NPs trigger interconnected mechanisms including NLRP3 inflammasome activation, oxidative stress ...
Alfi Sophian, Asmariani, Erika Ismayani
wiley +1 more source

