Results 271 to 280 of about 56,657 (298)
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Infective Proteins: The Prion Puzzle
Current Protein & Peptide Science, 2001According to the Koch postulates an infectious organism is the one that can be isolated from an host suffering from a disorder, can be propagated in laboratory, can cause the same disease when introduced in another host, and finally, can be re-isolated from the host itself.
F. Ceciliani, P. Pergami
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A Function for the Prion Protein?
2003Protein function is often observed directly following protein isolation, or is deduced by loss of function following gene knockout or by analogy with proteins of known function and similar amino acid sequence. None of these is true in the case of prion proteins because aside from the association with the pathogenesis of the spongiform encaphalopathies,
D R, Brown, I M, Jones
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Prion-like transmission of protein aggregates in neurodegenerative diseases
Nature Reviews Molecular Cell Biology, 2010Patrik Brundin +2 more
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Recombinant prion protein induces a new transmissible prion disease in wild-type animals
Acta Neuropathologica, 2010Natallia Makarava +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2019
Sonia M Vallabh +2 more
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Sonia M Vallabh +2 more
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Absence of the prion protein homologue Doppel causes male sterility
EMBO Journal, 2002Axel Behrens +2 more
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