Results 111 to 120 of about 14,426 (178)

The Exceptions to the Central Dogma of Biology—Bending the Rules and Extending the Scope

Natural Sciences, Volume 6, Issue 4, October 2026.
ABSTRACT The central dogma is an organizing framework for how information flows in biological systems. First presented in 1957 by Francis Crick in his talk “On Protein Synthesis” as a fundamental hypothesis of how information is transferred from DNA to proteins but not out of proteins, it is now introduced in cell biology textbooks as three sequential ...
Anat Ben‐Zvi
wiley   +1 more source

The axonal transport velocity of prions is independent of prion formation. [PDF]

PLoS Pathog
Koshy SM, Hrdlicka J, Nichols MG, Stender AS, Taylor JH, Castilla J, Bartz JC.   +6 more
europepmc   +1 more source

Modular Metalloprotein Nanowires With Semiconductor‐Scale Conductivity and Tunable Redox Behavior

Small Structures, Volume 7, Issue 10, October 2026.
Conductive protein nanowires are built by aligning three different metalloproteins along an ultrastable filament scaffold. The resulting micrometer‐length nanowires reach conductivities of 1.75 S cm−1. Redox behavior is set by the metalloprotein chosen, while conductivity is governed by the spacing the scaffold imposes, making both independently ...
Nga T. Lam, Lorenzo Travaglini, Yun X. Chen, Dominic J. Glover   +3 more
wiley   +1 more source

Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells. [PDF]

Proc Natl Acad Sci U S A
Rayner MLD, Arora P, Linehan JM, Ros H, Nihat A, Argentina F, Preston C, Schmidt C, Ribes JM, Klöhn PC, Mead S, Brandner S, Collinge J, Jat PS.   +13 more
europepmc   +1 more source

An Integrated Analysis of Manganese Metabolism‐Related Genes and Their Association With Biomarkers, Immune Infiltration, and Clinical Subtypes in Alzheimer's Disease

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
This study investigates the role of manganese metabolism in Alzheimer's disease (AD) pathogenesis. Using integrated bioinformatics and machine learning, four core manganese‐related diagnostic genes (TSPO, PTBP1, GLO1, ACACB) were identified, showing high diagnostic accuracy. The analysis also revealed significant immune microenvironment alterations and
Shengnan Shu, Jiahao Hu, Shanshan Hu, Yefeng Yao   +3 more
wiley   +1 more source

Distinct prion conformers from brain and peripheral tissues of gene-targeted mice produce convergent CWD strain properties. [PDF]

PLoS Pathog
DeFranco JP, Atkinson ZN, Crowell J, Shi X, Kim S, Sun JL, Kane SJ, Telling GC.   +7 more
europepmc   +1 more source

The Role of the Simulation in Supporting Newly Graduated Nurses in Their First 5 Months of Working Transition: Findings From a Mixed‐Method Study

Journal of Clinical Nursing, Volume 35, Issue 10, Page 4210-4220, October 2026.
ABSTRACT Aims To understand the role of simulation in ensuring the development of the competencies expected by newly graduated register nurses (NGRNs) from the work initiation up to 5 months of transition. Methods Mixed‐method study design. A longitudinal phase employing the Nurse Competence Scale (NCS, from 0 to 100, excellent) to assess the perceived
Maura Mesaglio, Sara Dentice, Luca Grassetti, Illarj Achil, Anna Bernardinis, Davide Caruzzo, Anna Inserra, Irene Mansutti, Elisa Mattiussi, Sandra Menegoz, Tommaso Piani, Elena Vanzo, Stefania Chiappinotto, Alvisa Palese   +13 more
wiley   +1 more source

Formic acid treatment drastically reduces sporadic Creutzfeldt-Jakob disease and variant Creutzfeldt-Jakob disease infectivity in histological samples as tested in a high-sensitivity mouse bioassay. [PDF]

J Gen Virol
Espinosa JC, Canoyra S, Fernández-Borges N, Marín-Moreno A, Torres JM.   +4 more
europepmc   +1 more source

Interferon-Stimulated Gene-Mediated Defense Against Prion Infection: Noncanonical Function of Oas1a. [PDF]

Viruses
Homma T, Ishibashi D.
europepmc   +1 more source

The protein disulfide isomerase P4HB/PDIA1 modulates cellular and misfolded forms of the prion protein. [PDF]

PLoS Pathog
Amano G, Arshad H, Patel Z, Schmitt-Ulms G, Watts JC.   +4 more
europepmc   +1 more source