Results 131 to 140 of about 48,246 (290)

Sugar Metabolisms Altered By Undissociated Forms of Organic Acids Based on the Emergence of [GAR+] Cells in Saccharomyces cerevisiae

Yeast, EarlyView.
ABSTRACT The glucose repression system is a mechanism for effective energy acquisition by glucose assimilation in microorganisms. In yeast, Saccharomyces cerevisiae, which is known as a prion‐like protein [GAR+], is involved in the bypass of glucose repression. It has been reported that the emergence of [GAR+] cells was promoted by lactate and acetate.
Koichi Tanabe, Atsuhiko Nakata, Mizuki Hosotani, Jun Shima   +3 more
wiley   +1 more source

Predicting disease spread from host movement data: Chronic wasting disease in North America as a case study

Journal of Animal Ecology, EarlyView.
This paper estimates the rate of chronic wasting disease spread in multiple regions and compares these rates with model predictions based on deer movement data. Abstract Rare long‐distance movements can increase the spatial spread of invasive species and shifts in species ranges. For wildlife disease spread, however, seasonal migrations may only matter
Paul C. Cross, Blake Lowrey, Matthew Kauffman, Evelyn Merrill   +3 more
wiley   +1 more source

Prions and prion diseases [PDF]

The FEBS Journal, 2007
openaire   +2 more sources

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Proceedings of the National Academy of Sciences of the United States of America, 2015
S. Prusiner, A. Woerman, Daniel A Mordes, J. Watts, R. Rampersaud, David B. Berry, Smita Patel, Abby Oehler, J. Lowe, Stephanie N. Kravitz, D. Geschwind, D. Glidden, G. Halliday, L. Middleton, S. Gentleman, L. Grinberg, K. Giles   +16 more
semanticscholar   +1 more source

Comments to the “Letter to the Editor” for the manuscript titled “Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease”

Brain Pathology, EarlyView.
Beta amyloid diffuse plaques, neurofibrillary tangles and neuritic plaques, are increased in densities at the intermediate stage of Alzheimer's neuropathological change. These pathological changes releasing Pathogen‐Associated Molecular Patterns (PAMPs) and Damage‐Associated Molecular Patterns (DAMPs).
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Nobel Lecture: Prions

, 1998
S. Prusiner
semanticscholar   +1 more source

Interlaboratory performance testing on EPIC v2.0 CNS tumor profiling demonstrates high reproducibility of tumor classification but reveals the need for harmonized copy number variation reporting

Brain Pathology, EarlyView.
Using the Infinium MethylationEPIC v2.0 array and Heidelberg Brain Tumor Classifier v12.8, 24 international laboratories achieved highly reproducible CNS tumor classification (97.9% correct; median β‐correlation r = 0.99), while copy number variation interpretation showed substantial interlaboratory variability, highlighting the need for harmonized CNV
Katrin Mauch‐Mücke, Christin Siewert, Lora Dimitrova, Sandra Pohl, Brendan Osberg, Annika K. Wefers, Julia Lorenz, Tanja Rothhammer‐Hampl, Till Acker, Alonso Barrantes‐Freer, Jean Boutonnat, Bérengère Dadone‐Montaudié, Claire Delbridge, Wolfgang Dietmaier, Sebastian Dintner, Hildegard Dohmen, Matthias Dottermusch, Daniel Erny, Katrin B. M. Frauenknecht, Tobias Goschzik, Patrick N. Harter, Daniela Hirsch, Yanghao Hou, Theo F. J. Kraus, Maggie Lee, Friederike Liesche‐Starnecker, Anne Mc Leer, Linea Melchior, Michael Mittelbronn, Wolf C. Müller, Shalima S. Nair, Julia E. Neumann, Pitt Niehusmann, Nicole Pfarr, Torsten Pietsch, Marco Prinz, Markus Rechsteiner, Regina Reimann, Laveniya Satgunaseelan, Veronica Skarpeteig, Anne J. Skjulsvik, Karl Sotlar, Isabelle Vanden Bempt, Erik Vassella, Katharina J. Weber, Gabriel Wasinger, Andreas Waha, Karen Zwaenepoel, Felix Sahm, Markus J. Riemenschneider, David Capper   +50 more
wiley   +1 more source

Direct prion neuroinvasion following inhalation into the nasal cavity

mSphere
Inhalation of prions into the nasal cavity is an efficient route of infection. Following inhalation of infectious prions, animals develop disease with a similar incubation period compared with per os exposure, but with greater efficiency. To identify the
Anthony E. Kincaid, Melissa D. Clouse, Shawn M. Magrum, Jason C. Bartz   +3 more
doaj   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Prions [PDF]

Current Biology, 1999
openaire   +2 more sources