Results 161 to 170 of about 71,281 (314)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Prions

open access: yesProceedings of the National Academy of Sciences, 1998
D, Westaway, G, Telling, S, Priola
openaire   +3 more sources

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

open access: yesClinical Anatomy, Volume 39, Issue 3, Page 346-367, April 2026.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Functions of J‐domain proteins in mitochondrial protein biogenesis

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Mitochondrial biogenesis and functions depend on the import and assembly of more than 1000 proteins that are made as precursors on cytosolic ribosomes. The majority of these precursor proteins are transported from the ribosome to the translocase of the outer membrane (TOM complex), which constitutes the main entry site for mitochondrial ...
Vitasta Tiku   +3 more
wiley   +1 more source

Prion disease [PDF]

open access: yesBritish Journal of Psychiatry, 1997
S, Fleminger, D, Curtis
openaire   +2 more sources

Toxic mechanisms of amyloid oligomers and therapeutic strategies

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Amyloid oligomers are increasingly recognized as the major toxic contributors across protein‐misfolding disorders. In this review, we cover mechanistic evidence showing how these transient and structurally heterogeneous oligomers disrupt cellular homeostasis by: (i) permeabilizing lipid membranes and forming ion‐conducting pores; (ii ...
Magdalena I. Ivanova   +2 more
wiley   +1 more source

MSA prions exhibit remarkable stability and resistance to inactivation

open access: yesActa Neuropathologica, 2017
A. Woerman   +11 more
semanticscholar   +1 more source

In vitro, cellular and in vivo studies of amyloid oligomers structure and toxicity: Challenges and advances

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Oligomeric assemblies of amyloidogenic proteins, such as Aβ, tau, α‐synuclein, amylin, transthyretin, and TDP‐43, are increasingly recognized as key drivers of cellular dysfunction across a range of neurodegenerative and systemic disorders.
Magdalena I. Ivanova   +2 more
wiley   +1 more source

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