Results 161 to 170 of about 56,806 (329)
The Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.Abstract Posdinemab, a humanized immunoglobulin G1/κ monoclonal antibody, binds with high affinity to phosphorylated tau protein which is associated with Alzheimer's disease (AD) pathophysiology. Posdinemab reduced tau seeding in murine models and was well tolerated in Phase‐1 clinical studies.
Fangfang Wang +7 more
wiley +1 more source
Heat shock protein 10 as a chaperone modulating α‐synuclein amyloid fibril formation
Protein Science, Volume 35, Issue 2, February 2026.Abstract HSP10 is a well‐known human co‐chaperone that interacts with HSP60 to comprise the HSP60/10 chaperonin complex which upholds mitochondrial proteostasis. HSP10 also demonstrates independent roles in binding to misfolded proteins and interacts with several amyloidogenic client proteins.
Johan N. K. Larsson +5 more
wiley +1 more source
Specific Features of the Prion Protein Transmembrane Domain Regulate Nascent Chain Orientation [PDF]
, 2007 Carolyn M. Ott +2 more
openalex +1 more source
Protein Science, Volume 35, Issue 2, February 2026.Abstract Spider silks are proteinaceous fiber materials inspiring material design in various technical and biomedical fields due to their exceptional toughness, which exceeds that of most natural and artificial fibers. Solid‐state nuclear magnetic resonance (NMR) spectroscopy has been used herein to obtain insights into the structure and dynamics of ...
Nina Wehr +6 more
wiley +1 more source