Results 161 to 170 of about 37,766 (292)

PRION DISEASES [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2004
R S G, Knight, R G, Will
openaire   +3 more sources

A composition‐matching algorithm, MatchIDR, identifies prion‐like domains that localize to stress granules

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Intrinsically disordered regions (IDRs) play important molecular roles in cells even though they do not adopt a stable structure. Relative to structured regions, IDRs have skewed amino acid compositions favoring polar and charged amino acids. This feature is a major contributor to the biophysical behavior and in vivo activity of IDRs, but the ...
Sean M. Cascarina   +3 more
wiley   +1 more source

Prions, prions everywhere [PDF]

open access: yesNature Reviews Neuroscience, 2003
openaire   +1 more source

A Review of Metal–Organic Framework (MOF) Based Active Food Packaging: Materials Selection, Cellulose Matrices Current Advances, Synthesis and Characterizations

open access: yesPackaging Technology and Science, Volume 39, Issue 5, Page 533-572, May 2026.
Active packaging offers an effective approach to extending food shelf life. This review summarizes the past decade of progress in metal‐organic framework (MOF)‐based active food packaging, highlighting material selection, characterization, challenges, and future prospects.
Belladini Lovely   +4 more
wiley   +1 more source

Evidence for different seeding activities of misfolded tau in classical and rapidly progressive Alzheimer's disease

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
The study analyzed the seeding activity of misfolded tau protein in Alzheimer's disease and rapidly progressive Alzheimer's disease patients and provides evidence for the existence of different tau assemblies supported by differences in cellular toxicity and morphology of thioflavin T‐positive real‐time quaking‐induced conversion products.
Matthias Schmitz   +13 more
wiley   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown   +7 more
wiley   +1 more source

Narrative review of strategies for blood product shelf‐life extension

open access: yes
Transfusion, EarlyView.
Mike Akaraphanth   +7 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 827-833, April 2026.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro   +10 more
wiley   +1 more source

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 4, Page 845-849, April 2026.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow   +4 more
wiley   +1 more source

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