Results 291 to 300 of about 5,438,748 (355)

Patient, family and clinician priorities for critical care research in Asia and Africa: a James Lind Alliance Priority Setting Partnership using modified Delphi and nominal group techniques. [PDF]

open access: yesBMJ Glob Health
CCAA Priority Setting Partnership Steering group   +25 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Model rural health research units in India: A research priority setting exercise. [PDF]

open access: yesIndian J Med Res
Kshatri JS   +11 more
europepmc   +1 more source

Cocreating research priorities for anorexia nervosa: The Canadian Eating Disorder Priority Setting Partnership.

International Journal of Eating Disorders, 2020
OBJECTIVE The Canadian Eating Disorder Priority Setting Partnership was established to identify and prioritize the top 10 research priorities for females, 15 years or older, with anorexia nervosa, by incorporating equal input from those with lived ...
N. Obeid   +4 more
semanticscholar   +1 more source

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