Results 121 to 130 of about 251,912 (281)

Long‐term association of physical activity with survival by primary cancer treatment in endometrial cancer: The Alberta Endometrial Cancer Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Accumulating evidence suggests a beneficial role of physical activity in cancer. However, it is unclear whether associations between physical activity and cancer outcomes vary by cancer treatment. Based on more than 16 years of follow‐up data from a cohort of endometrial cancer survivors, this study reveals that associations between ...
Minsuk Oh   +7 more
wiley   +1 more source

PRL, teatr, rewolucja

open access: yesWidok. Teorie i Praktyki Kultury Wizualnej, 2016
Recenzja książki Joanny Krakowskiej "PRL. Przedstawienia" (Warszawa 2016).
openaire   +1 more source

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

open access: yesPLoS ONE, 2011
Combination with other small molecule drugs represents a promising strategy to improve therapeutic efficacy of FLT3 inhibitors in the clinic. We demonstrated that combining ABT-869, a FLT3 inhibitor, with SAHA, a HDAC inhibitor, led to synergistic ...
Jianbiao Zhou   +13 more
semanticscholar   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang   +11 more
wiley   +1 more source

Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion

open access: yesOncogene, 2011
The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeutic targets. Although several studies have documented that altered expression of
Yan Wang, J. Lazo
semanticscholar   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration

open access: yesExperimental Hematology & Oncology, 2018
Background Phosphatase of regenerating liver-3 (PRL-3) is implicated in oncogenesis of hematological and solid cancers. PRL-3 expression increases metastatic potential, invasiveness and is associated with poor prognosis. With this study, we aimed to show
Magnus Aassved Hjort   +8 more
doaj   +1 more source

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo   +5 more
wiley   +1 more source

Topological Photonic Devices and Circuits at Terahertz Frequencies

open access: yesLaser &Photonics Reviews, EarlyView.
This review examines how 3D topological insulators and emerging topological photonic phases enable robust, low‐loss and defect‐immune terahertz devices. Fundamental properties, device implementations and topological transport mechanisms are surveyed, revealing new opportunities for reconfigurable, high‐performance THz components and scalable ...
Samane Kalhor   +3 more
wiley   +1 more source

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

open access: yesThe Journal of Pathology, EarlyView.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen   +14 more
wiley   +1 more source

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