Results 101 to 110 of about 111,764 (305)

„Cała Polska stoi dziś w kolejkach". Powieści Konwickiego jako źródło do badania codzienności PRL-u

Litteraria Copernicana, 2008
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Piotr Perkowski
doaj   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Characterization of Chicken Prolactin Regulatory Element Binding Protein and its Expression in the Anterior Pituitary Gland during Embryogenesis and Different Reproductive Stages

The Journal of Poultry Science, 2015
The PRL regulatory element binding protein (PREB) is a transcription factor that specifically binds to a Pit-1 binding element in the PRL promoter to regulate PRL gene expression in mammals.
Gen Hiyama, Norio Kansaku, Toshio Tanaka, Shin Wakui, David Zadworny   +4 more
doaj   +1 more source

Reputación en PRL

, 2023
Reputación en PRL AUTOR: José Javier Miranda Mayo La valoración de los grupos de interés y de la sociedad en general de las empresas, es un elemento clave para generar importantes valores intangibles como la reputación empresarial.
josé javier miranda mayo
core  

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Effects of Vasoactive Intestinal Polypeptide and Forskolin on mRNA Expression of Prolactin and Prolactin Regulatory Element-Binding Protein in the Anterior Pituitary Gland of Chicken Embryo and Laying Hens

The Journal of Poultry Science, 2016
Vasoactive intestinal peptide (VIP) treatment induced mRNA expression of Prolactin (PRL) in the chicken anterior pituitary gland. VIP responsive element (VRE) of the PRL promoter was identified in the various bird species. However, transcription factor,
Norio Kansaku, Yasuko Tobari, Gen Hiyama, Shin Wakui, Naokazu Minoguchi, Masazumi Numata, Katsutoshi Kino, David Zadworny   +7 more
doaj   +1 more source

PRL deficiency results in hippocampal learning defects.

, 2013
(A) The PRL null mice spent significantly less time in the novel arm of a Y-maze compared to their wild-type littermates ...
Tara L. Walker (308979), Eirinn W. Mackay (308981), Daniel G. Blackmore (297180), Margaretha M. Koudijs (308980), Adam S. Hamlin (289993), Rupert W. Overall (122762), Perry F. Bartlett (205720), Jana Vukovic (297181), Alex M. Sykes (308982)   +8 more
core   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Równouprawnienie płci w debacie parlamentarnej Sejmu Ustawodawczego 1947–1952. Zarys problemu

Acta Universitatis Lodziensis: Folia Sociologica, 2019
Artykuł zawiera analizę charakteru debaty sejmowej dotyczącej równouprawnienia kobiet i mężczyzn, z uwzględnieniem problematyki ochrony praw dzieci, która toczyła się w Sejmie Ustawodawczym RP w latach 1947–1952.
Edyta Chrobaczyńska-Plucińska
doaj   +1 more source